prikaz prve stranice dokumenta Incidence and risk factors for moderate and severe bronchopulmonary dysplasia in very low birth weight infants in two Croatian perinatal regions - a retrospective cohort study
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Scientific paper - Original scientific paper
Incidence and risk factors for moderate and severe bronchopulmonary dysplasia in very low birth weight infants in two Croatian perinatal regions - a retrospective cohort study
Journal of Pediatric and Neonatal Individualized Medicine, 8 (2019), 1; 080129. https://doi.org/10.7363/080129
Kardum, Darjan; Filipović Grčić, Boris; Mueller, Andrijana; Dessardo, Sandro

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Kardum, D., Filipović Grčić, B., Mueller, A. & Dessardo, S. (2019). Incidence and risk factors for moderate and severe bronchopulmonary dysplasia in very low birth weight infants in two Croatian perinatal regions - a retrospective cohort study. Journal of Pediatric and Neonatal Individualized Medicine, 8. (1). doi: 10.7363/080129

Kardum, Darjan, et al. "Incidence and risk factors for moderate and severe bronchopulmonary dysplasia in very low birth weight infants in two Croatian perinatal regions - a retrospective cohort study." Journal of Pediatric and Neonatal Individualized Medicine, vol. 8, no. 1, 2019. https://doi.org/10.7363/080129

Kardum, Darjan, Boris Filipović Grčić, Andrijana Mueller and Sandro Dessardo. "Incidence and risk factors for moderate and severe bronchopulmonary dysplasia in very low birth weight infants in two Croatian perinatal regions - a retrospective cohort study." Journal of Pediatric and Neonatal Individualized Medicine 8, no. 1 (2019). https://doi.org/10.7363/080129

Kardum, D., et al. (2019) 'Incidence and risk factors for moderate and severe bronchopulmonary dysplasia in very low birth weight infants in two Croatian perinatal regions - a retrospective cohort study', Journal of Pediatric and Neonatal Individualized Medicine, 8(1). doi: 10.7363/080129

Kardum D, Filipović Grčić B, Mueller A, Dessardo S. Incidence and risk factors for moderate and severe bronchopulmonary dysplasia in very low birth weight infants in two Croatian perinatal regions - a retrospective cohort study. Journal of Pediatric and Neonatal Individualized Medicine [Internet]. 2019 [cited 2025 January 14];8(1). doi: 10.7363/080129

D. Kardum, B. Filipović Grčić, A. Mueller and S. Dessardo, "Incidence and risk factors for moderate and severe bronchopulmonary dysplasia in very low birth weight infants in two Croatian perinatal regions - a retrospective cohort study", Journal of Pediatric and Neonatal Individualized Medicine, vol. 8, no. 1, 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:812720. [Accessed: 14 January 2025]

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Metadata
Title (english)Incidence and risk factors for moderate and severe bronchopulmonary dysplasia in very low birth weight infants in two Croatian perinatal regions - a retrospective cohort study
AuthorDarjan Kardum
AuthorBoris Filipović Grčić
AuthorAndrijana Mueller
AuthorSandro Dessardo
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Pediatrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Abstract (english)
Introduction: Bronchopulmonary dysplasia (BPD) is a significant cause of mortality and morbidity in preterm infants. The incidence of BPD varies widely between centers and is found in 20% to 40% of very low birth weight (VLBW) infants. Our work aimed to examine the incidence and risk factors for moderate and severe BPD in a population of VLBW infants. Materials and methods: Demographic data, risk factors, incidence and severity of BPD were analyzed for 178 VLBW infants treated in two Croatian perinatal regions (2 level III neonatal units, 2 level II neonatal units and 5 level I neonatal wards) in the period from January 1, 2014 to December 31, 2016. Results: The rate of BPD was 59.6% (106/178) which is significantly higher than reported earlier. Mild BPD accounted for 65.1% (69/106) and moderate/severe BPD is found in 34.9% (37/106) infants. Among infants with ≤ 28 weeks of gestation, the rate of moderate and severe BPD was 40.5% (30/74). Ultimate risk factors for the development of moderate/severe BPD were late-onset sepsis (p = 0.03 ; OR [95% CI]: 4.76 [1.22-18.5]), and higher initial neonatal risk as expressed by Critical Risk Index for Babies (CRIB) score (p < 0.001 ; OR [95% CI]: 1.73 [1.32- 2.29]). Conclusion: The incidence of moderate and severe BPD in our study group is higher than previously reported, and the majority of affected infants are < 29 weeks of gestation. The factors that had the strongest influence on the development of moderate and severe BPD were a higher initial neonatal risk as expressed by CRIB score and late-onset sepsis.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleJournal of Pediatric and Neonatal Individualized Medicine
Numberingvol. 8, no. 1, 080129
p-ISSN2281-0692
DOIhttps://doi.org/10.7363/080129
URN:NBNurn:nbn:hr:184:812720
Publication2019
Document URLhttp://bib.irb.hr/1049176
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-02-23 09:23:01