prikaz prve stranice dokumenta Cytomegalovirus Seroprevalence and Birth Prevalence of Congenital CMV Infection in Bosnia and Herzegovina : A Single-Center Experience
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Scientific paper - Original scientific paper
Cytomegalovirus Seroprevalence and Birth Prevalence of Congenital CMV Infection in Bosnia and Herzegovina : A Single-Center Experience
The Pediatric Infectious Disease Journal, 39 (2020), 2; 140-144. https://doi.org/10.1097/inf.0000000000002510
Arapović, Jurica; Rajič, Borko; Pati, Sunil; Brizić, Ilija; Azinović, Igor; Šušak, Božo; Ostojić, Maja; Tutiš, Borka; Raguž, Ana Boban; Tomić, Vajdana; Jonjić, Stipan; Boppana, Suresh

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Arapović, J., Rajič, B., Pati, S., Brizić, I., Azinović, I., Šušak, B. ... Boppana, S. (2020). Cytomegalovirus Seroprevalence and Birth Prevalence of Congenital CMV Infection in Bosnia and Herzegovina : A Single-Center Experience. The Pediatric Infectious Disease Journal, 39. (2), 140-144. doi: 10.1097/inf.0000000000002510

Arapović, Jurica, et al. "Cytomegalovirus Seroprevalence and Birth Prevalence of Congenital CMV Infection in Bosnia and Herzegovina : A Single-Center Experience." The Pediatric Infectious Disease Journal, vol. 39, no. 2, 2020, pp. 140-144. https://doi.org/10.1097/inf.0000000000002510

Arapović, Jurica, Borko Rajič, Sunil Pati, Ilija Brizić, Igor Azinović, Božo Šušak, Maja Ostojić, et al. "Cytomegalovirus Seroprevalence and Birth Prevalence of Congenital CMV Infection in Bosnia and Herzegovina : A Single-Center Experience." The Pediatric Infectious Disease Journal 39, no. 2 (2020): 140-144. https://doi.org/10.1097/inf.0000000000002510

Arapović, J., et al. (2020) 'Cytomegalovirus Seroprevalence and Birth Prevalence of Congenital CMV Infection in Bosnia and Herzegovina : A Single-Center Experience', The Pediatric Infectious Disease Journal, 39(2), pp. 140-144. doi: 10.1097/inf.0000000000002510

Arapović J, Rajič B, Pati S, Brizić I, Azinović I, Šušak B, and sur.. Cytomegalovirus Seroprevalence and Birth Prevalence of Congenital CMV Infection in Bosnia and Herzegovina : A Single-Center Experience. The Pediatric Infectious Disease Journal [Internet]. 2020 [cited 2024 April 26];39(2):140-144. doi: 10.1097/inf.0000000000002510

J. Arapović, et al., "Cytomegalovirus Seroprevalence and Birth Prevalence of Congenital CMV Infection in Bosnia and Herzegovina : A Single-Center Experience", The Pediatric Infectious Disease Journal, vol. 39, no. 2, pp. 140-144, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:825892. [Accessed: 26 April 2024]

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Metadata
Title (english)Cytomegalovirus Seroprevalence and Birth Prevalence of Congenital CMV Infection in Bosnia and Herzegovina : A Single-Center Experience
AuthorJurica Arapović
AuthorBorko Rajič
AuthorSunil Pati
AuthorIlija Brizić
AuthorIgor Azinović
AuthorBožo Šušak
AuthorMaja Ostojić
AuthorBorka Tutiš
AuthorAna Boban Raguž
AuthorVajdana Tomić
AuthorStipan Jonjić
AuthorSuresh Boppana
Author's institutionUniversity of Rijeka
Faculty of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Background: Congenital cytomegalovirus infection (cCMV) is a leading cause of sensorineural hearing loss (SNHL) and neurodevelopmental disabilities in developed countries. Although high cCMV rates have been reported in populations with high seroprevalence, the cCMV prevalence in low/middle-income countries in Europe has not been defined. Objective: To determine cytomegalovirus (CMV) seroprevalence and the cCMV prevalence in Bosnia and Herzegovina. Methods: Between March 2010 and February 2019, 5222 sera samples from patients seen at the University Clinical Hospital Mostar were tested for CMV IgG. The cord blood samples collected from 2091 infants between July 2011 and January 2013 were analyzed for CMV IgG and CMV DNA. The cCMV prevalence was determined by testing saliva swabs from 1293 infants between November 2015 and October 2016. Results: The overall CMV IgG prevalence was 81.4% (95% confidence interval: 0.8-0.82). Significantly higher prevalence was observed among females (84.9%) than in males (77.0%), and the rate increased from 50.8% in the 1 to 5 years group to 97.7% in the group > 65 years old. Most cord blood samples (2091/1925, 92.1%) were CMV IgG positive, and 2 (0.1%) were CMV DNA positive. Of the 1293 saliva swabs, 8 (0.62% ; 95% confidence interval: 0.3-1.2) were CMV positive. All 8 infected infants had asymptomatic cCMV, and none had SNHL at 18 months of age. Conclusions: In a highly CMV seropositive population, the prevalence of cCMV was lower compared with that reported from other low/middle-income countries populations. None of the infected infants had symptomatic infection or SNHL at 18 months.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleThe Pediatric Infectious Disease Journal
Numberingvol. 39, no. 2, pp. 140-144
p-ISSN0891-3668
DOIhttps://doi.org/10.1097/inf.0000000000002510
URN:NBNurn:nbn:hr:184:825892
Publication2020
Document URLhttp://bib.irb.hr/1107475
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2022-02-15 14:35:35