Endocrine disorders, through deficiencies or excess of hormones, lead to various changes in cutaneous function and morphology that result in numerous and complex symptomatology. Cutaneous manifestations of diabetes include acanthosis nigricans, limited joint mobility and scleroderma-like syndrome, scleredema diabeticorum, eruptive xanthomas, diabetic foot, necrobiosis lipoidica, granuloma annulare, diabetic dermopathy and bullosis diabeticorum. The classic sign of hyperthyroidism is thyroid dermopathy. Besides that, skin is warm and velvety, hair is thin and nails become soft, shiny and brittle. Myxedema is a classic manifestation of hypothyroidism. Alopecia may be present while there is regularly dry and hyperkeratotic skin. Calcinosis cutis and calciphylaxis rarely occur in hyperparathyroidism whereas hypoparathyroidism is associated with scaly, hyperkeratotic and edematous skin. Violaceous striae on abdomen are pathognomonic of Cushing syndrome. Other clinical findings include skin atrophy and hyperpigmentation. Hyperpigmenation is the main cutaneous manifestation of Addison disease. Hypoestrogenism causes xerotic and atrophic skin, while hyperestrogenism has the opposite effect. Melasma can be associated with estrogen excess. Androgen excess can cause sudden onset of acne, hirsutism and androgenetic alopecia. Acromegaly manifests with thickened skin, eyelids, lips and nose, with deep grooves on the face, excessive sweating, hisutism and acanthosis nigricans. Patients with hypopituitarism are characterizied by pale and atrophic skin and loss of pubic and axillary hair. Treatment of cutaneous manifestations of endocrine disorders is mostly specific and etiologic. In cases of hormone deficiency, that means replacement therapy of hormones. The primary treatment of hormone excess includes surgical procedures