prikaz prve stranice dokumenta Baseline ICIQ-UI score, body mass index, age, average birth weight, and perineometry duration as promising predictors of the short-term efficacy of Er:YAG laser treatment in stress urinary incontinent women: A prospective cohort study
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Scientific paper - Original scientific paper
Baseline ICIQ-UI score, body mass index, age, average birth weight, and perineometry duration as promising predictors of the short-term efficacy of Er:YAG laser treatment in stress urinary incontinent women: A prospective cohort study
Lasers in Surgery and Medicine, 50 (2018), 6; 636-643. https://doi.org/10.1002/lsm.22789
Fistonić, Ivan; Fistonić, Nikola

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Fistonić, I. & Fistonić, N. (2018). Baseline ICIQ-UI score, body mass index, age, average birth weight, and perineometry duration as promising predictors of the short-term efficacy of Er:YAG laser treatment in stress urinary incontinent women: A prospective cohort study. Lasers in Surgery and Medicine, 50. (6), 636-643. doi: 10.1002/lsm.22789

Fistonić, Ivan and Nikola Fistonić. "Baseline ICIQ-UI score, body mass index, age, average birth weight, and perineometry duration as promising predictors of the short-term efficacy of Er:YAG laser treatment in stress urinary incontinent women: A prospective cohort study." Lasers in Surgery and Medicine, vol. 50, no. 6, 2018, pp. 636-643. https://doi.org/10.1002/lsm.22789

Fistonić, Ivan and Nikola Fistonić. "Baseline ICIQ-UI score, body mass index, age, average birth weight, and perineometry duration as promising predictors of the short-term efficacy of Er:YAG laser treatment in stress urinary incontinent women: A prospective cohort study." Lasers in Surgery and Medicine 50, no. 6 (2018): 636-643. https://doi.org/10.1002/lsm.22789

Fistonić, I. and Fistonić, N. (2018) 'Baseline ICIQ-UI score, body mass index, age, average birth weight, and perineometry duration as promising predictors of the short-term efficacy of Er:YAG laser treatment in stress urinary incontinent women: A prospective cohort study', Lasers in Surgery and Medicine, 50(6), pp. 636-643. doi: 10.1002/lsm.22789

Fistonić I, Fistonić N. Baseline ICIQ-UI score, body mass index, age, average birth weight, and perineometry duration as promising predictors of the short-term efficacy of Er:YAG laser treatment in stress urinary incontinent women: A prospective cohort study. Lasers in Surgery and Medicine [Internet]. 2018 [cited 2024 December 25];50(6):636-643. doi: 10.1002/lsm.22789

I. Fistonić and N. Fistonić, "Baseline ICIQ-UI score, body mass index, age, average birth weight, and perineometry duration as promising predictors of the short-term efficacy of Er:YAG laser treatment in stress urinary incontinent women: A prospective cohort study", Lasers in Surgery and Medicine, vol. 50, no. 6, pp. 636-643, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:725429. [Accessed: 25 December 2024]

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Title (english)Baseline ICIQ-UI score, body mass index, age, average birth weight, and perineometry duration as promising predictors of the short-term efficacy of Er:YAG laser treatment in stress urinary incontinent women: A prospective cohort study
AuthorIvan Fistonić
AuthorNikola Fistonić
Author's institutionUniversity of Rijeka
Faculty of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
BACKGROUND AND OBJECTIVE: A growing body of evidence indicates that a non-invasive erbium yttrium-aluminum-garnet (Er:YAG) laser may be an effective and highly tolerable treatment for stress urinary incontinence (SUI) in women. The primary objective was to identify pre-intervention predictors of short-term Er:YAG outcomes. The secondary objective was to identify patient segments with the best Er:YAG laser treatment short-term outcomes. METHODS: A prospective cohort study performed in 2016 at Ob/Gyn Clinic, Zagreb, Croatia, recruited 85 female patients who suffered from SUI. The intervention was performed with a 2940 nm wave length Er:YAG laser (XS Dynamis, Fotona, Slovenia). Outcomes were absolute change in the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-UI SF) and a relative decrease in ICIQ-UI score of ≥30% 2-6 months after the intervention. RESULTS: Age and pre-intervention ICIQ-UI values were independent significant predictors of laser treatment efficacy for SUI. A decrease in ICIQ-UI score (minimum important difference, MID) of ≥30% was independently significantly associated with body mass index and ICIQ-UI values before the intervention. All patients with four or five positive predictors saw a clinically relevant decrease in ICIQ-UI of ≥30%. The total accuracy of the predictive model defined by the area under the curve was 0.83 (95%CI 0.74-0.91). At the cut-off ≥3 positive predictors, C-index was 0.80 (95%CI 0.71-0.90), positive predictive value was 0.97 (95%CI 0.87-0.99), and negative predictive value was 0.53 (95%CI 0.45-0.55). CONCLUSIONS: A relevant decrease in ICIQ-UI (MID) of ≥30% can be predicted based on age, body mass index, average birth weight, perineometer squeeze duration, and ICIQ-UI scores before the intervention. The association between Q-tip test and treatment outcome was moderated by age. Q-tip was a significant predictor for patients between 44 and 53 years of age. The best results should be expected in younger women with a body mass index of ≤23.3, average birth weight of >3.6 kg, ICIQ-UI at a baseline of ≤10, and perineometer squeeze duration at a baseline of ≥3.51 seconds. The critical age for Er:YAG laser effect is 47.5 years
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleLasers in Surgery and Medicine
Numberingvol. 50, no. 6, pp. 636-643
p-ISSN0196-8092
DOIhttps://doi.org/10.1002/lsm.22789
URN:NBNurn:nbn:hr:184:725429
Publication2018
Document URLhttp://bib.irb.hr/1049621
Type of resourceText
Access conditionsRestricted access
Terms of useLicence In copyright icon
Created on2022-02-08 14:17:55