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Scientific paper - Original scientific paper
(Charge fluctuations in plasma) An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45
Annals of Oncology, 31 (2020), 2; 283-288. https://doi.org/10.1016/j.annonc.2019.10.027
Bjelić-Radišić, V.; Cardoso, F.; Cameron, D.; Brain, E.; Kuljanić, Karin; da Costa, R.A.; Conroy, T.; Inwald, E.C.; Serpentini, S.; Pinto, M.; Weis, J.; Morag, O.; Lindviksmoen Astrup, G.; Tomaszweksi, K.A.; Pogoda, K.; Sinai, P.; Sprangers, M.; Aaronson, N.; Velikova, G.; Greimel, E.; Arraras, J.; Bottomley, A.; Bleiker, Eveline; Bliem, Brigitte; Chie, Weichu; Creutzberg, Carien; Deville, Valerie; Duhoux, Francois; Eilf, Kirsten; Hartup, Sue; Koller, Michael; Nagele, Eva; Nicolatou-Galitis, Ourania; Oberguggenberger, Anne; Schmalz, Claudia; Winters, Zoe More authors...

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Bjelić Radišić, V., Cardoso, F., Cameron, D., Brain, E., Kuljanić, K., da Costa, R. ... Winters, Z. (2020). (Charge fluctuations in plasma) An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45. Annals of Oncology, 31. (2), 283-288. doi: 10.1016/j.annonc.2019.10.027

Bjelić Radišić, V., et al. "(Charge fluctuations in plasma) An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45." Annals of Oncology, vol. 31, no. 2, 2020, pp. 283-288. https://doi.org/10.1016/j.annonc.2019.10.027

Bjelić Radišić, V., F. Cardoso, D. Cameron, E. Brain, Karin Kuljanić, R.A. da Costa, T. Conroy, et al. "(Charge fluctuations in plasma) An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45." Annals of Oncology 31, no. 2 (2020): 283-288. https://doi.org/10.1016/j.annonc.2019.10.027

Bjelić Radišić, V., et al. (2020) '(Charge fluctuations in plasma) An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45', Annals of Oncology, 31(2), pp. 283-288. doi: 10.1016/j.annonc.2019.10.027

Bjelić Radišić V, Cardoso F, Cameron D, Brain E, Kuljanić K, da Costa R, and sur.. (Charge fluctuations in plasma) An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45. Annals of Oncology [Internet]. 2020 [cited 2024 November 13];31(2):283-288. doi: 10.1016/j.annonc.2019.10.027

V. Bjelić Radišić, et al., "(Charge fluctuations in plasma) An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45", Annals of Oncology, vol. 31, no. 2, pp. 283-288, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:899624. [Accessed: 13 November 2024]

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Title (english)(Charge fluctuations in plasma) An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45
Title (english)An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45
AuthorV. Bjelić-Radišić
AuthorF. Cardoso
AuthorD. Cameron
AuthorE. Brain
AuthorKarin Kuljanić
AuthorR.A. da Costa
AuthorT. Conroy
AuthorE.C. Inwald
AuthorS. Serpentini
AuthorM. Pinto
AuthorJ. Weis
AuthorO. Morag
AuthorG. Lindviksmoen Astrup
AuthorK.A. Tomaszweksi
AuthorK. Pogoda
AuthorP. Sinai
AuthorM. Sprangers
AuthorN. Aaronson
AuthorG. Velikova
AuthorE. Greimel
AuthorJ. Arraras
AuthorA. Bottomley
AuthorEveline Bleiker
AuthorBrigitte Bliem
AuthorWeichu Chie
AuthorCarien Creutzberg
AuthorValerie Deville
AuthorFrancois Duhoux
AuthorKirsten Eilf
AuthorSue Hartup
AuthorMichael Koller
AuthorEva Nagele
AuthorOurania Nicolatou-Galitis
AuthorAnne Oberguggenberger
AuthorClaudia Schmalz
AuthorZoe Winters
Author's institutionUniversity of Rijeka
Faculty of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Scientific / art field,
discipline and subdiscipline		SOCIAL SCIENCES
Psychology
Abstract (english)
Background: The European Organization for Research and Treatment of Cancer (EORTC) QLQ- BR23 was one of the first disease-specific questionnaires developed in 1996 to assess quality of life (QoL) in patients with breast cancer (BC). However, since 1996 major changes in BC treatment have occurred, requiring an update of the EORTC BC module. This study presents the results of the phase I–III update of the QLQ-BR23 questionnaire. Patients and methods: The update of the EORTC QLQ-BR23 module followed standard EORTC guidelines. A systematic literature review revealed 83 potential relevant QoL issues during phases I and II. After shortening the issues list and following interviews with patients and health care providers, 15 relevant issues were transformed into 27 items. The preliminary module was pretested in an international, multicentre phase III study to identify and solve potential problems with wording comprehensibility and acceptability of the items. Descriptive statistics are provided. Analyses were qualitative and quantitative. We provide a psychometric structure of the items. Results: The phase I and II results indicated the need to supplement the original QLQ-BR23 with additional items related to newer therapeutic options. The phase III study recruited a total of 250 patients (from 12 countries). The final updated phase III module contains a total of 45 items: 23 items from the QLQ-BR23 and 22 new items. The new items contain two multi-item scales: a target symptom scale and a satisfaction scale. The target symptom scale can be divided into three subscales: endocrine therapy, endocrine sexual and skin/mucosa scale. Conclusion: Our work has led to the development of a new EORTC QLQ-BR45 module that provides a more accurate and comprehensive assessment of the impact of new and scalable treatments on patients' QoL. The final version of the EORTC QLQ-BR45 is currently available for use in clinical practice. The final phase IV study is underway to confirm psychometric properties of the module. © 2019 European Society for Medical Oncology
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleAnnals of Oncology
Numberingvol. 31, no. 2, pp. 283-288
p-ISSN0923-7534
DOIhttps://doi.org/10.1016/j.annonc.2019.10.027
URN:NBNurn:nbn:hr:184:899624
Publication2020
Document URLhttp://bib.irb.hr/1109922
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-02-07 12:52:55