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master's thesis
Izvancrijevne manifestacije upalnih bolesti crijeva
2021. urn:nbn:hr:184:783144
Višić, Marin
University of Rijeka
Faculty of Medicine
Department of Internal Medicine

Cite this document

Višić, M. (2021). Izvancrijevne manifestacije upalnih bolesti crijeva (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:783144

Višić, Marin. "Izvancrijevne manifestacije upalnih bolesti crijeva." Master's thesis, University of Rijeka, Faculty of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:184:783144

Višić, Marin. "Izvancrijevne manifestacije upalnih bolesti crijeva." Master's thesis, University of Rijeka, Faculty of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:184:783144

Višić, M. (2021). 'Izvancrijevne manifestacije upalnih bolesti crijeva', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 16 April 2025, https://urn.nsk.hr/urn:nbn:hr:184:783144

Višić M. Izvancrijevne manifestacije upalnih bolesti crijeva [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2021 [cited 2025 April 16] Available at: https://urn.nsk.hr/urn:nbn:hr:184:783144

M. Višić, "Izvancrijevne manifestacije upalnih bolesti crijeva", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:184:783144

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Metadata
TitleIzvancrijevne manifestacije upalnih bolesti crijeva
Title (english)Extraintestinal manifestations of inflammatory bowel diseases
AuthorMarin Višić
MentorVanja Licul (mentor)
Committee memberBrankica Mijandrušić-Sinčić (predsjednik povjerenstva)
Committee memberSanja Klobučar-Majanović (član povjerenstva)
Committee memberGoran Poropat (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Rijeka
Defense date and country2021-07-16, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
U spektru upalnih bolesti crijeva (UBC) spadaju ulcerozni kolitis, Crohnova bolesti i neklasificirana upalna bolest crijeva. Ulcerozni kolitis je kronična upalna bolest sluznice rektuma i debelog crijeva. Crohnova bolest je karakterizirana transmuralnom upalom koja može zahvatiti bilo koji dio lumena gastrointestinalnog trakta od usne šupljine do perianalnog područja. Neklasificirana upalna bolest crijeva je termin koji se koristi kada bolest ne zadovoljava uobičajne kriterije za ulcerozni... More kolitis ili Crohnovu bolest uz ponavljane kolonoloskopije i biopsije. Smatra se da se u patogenezi bolesti nalaze kompleksne interakcije između genetike, čimbenika rizika, crijevne mikrobiote i imunosnog odgovora. UBC su sistemske bolesti koje nisu ograničene na gastrointestinalni trakt te utječu na mnoge organske sustave. Izvancrijevne manifestacije (EIM) najčešće zahvaćaju muskuloskeletni sustav, kožu, hepatobilijarni trakt, oči, sluznice te rijeđe pluća, gušteraču, bubrege, živčani i kardiovaskularni sustav. 50% bolesnika tijekom života razvije barem jednu EIM, ponekad čak i prije postavljanja dijagnoze. Neke EIM su izravno povezane s aktivnošću osnovne bolesti (artritis, aftozni stomatitis, nodozni eritem i episkleritis), neke imaju neovisni tijek (ankilozantni spondilitis, uveitis), a neke mogu i ne moraju biti povezane s aktivnošću bolesti (primarni sklerozirajući kolangitis, gangrenozna pioderma). Simptomi EIM mogu biti vrlo iscrpljujući. Kod EIM koje prate aktivnost UBC, za olakšanje simptoma često je dovoljna optimalna terapija za UBC uz pažljivo praćenje pacijenta. EIM koje su neovisne o aktivnosti UBC mogu zahtijevati multidisciplinarni tim i dodatnu terapiju. Less
Abstract (english)
The spectrum of inflammatory bowel diseases includes ulcerative colitis, Crohn’s disease, and unclassified inflammatory bowel disease. Ulcerative colitis is a chronic inflammatory disease of the lining mucosa of the rectum and colon. Crohn's disease is characterized by transmural inflammation that can affect any part of the lumen of the gastrointestinal tract from the oral cavity to the perianal area. Unclassified inflammatory bowel disease is a term used when the disease does not meet... More the usual criteria for ulcerative colitis or Crohn’s disease with repeated colonoscopies and biopsies. The pathogenesis of the disease is thought to involve complex interactions between genetics, risk factors, intestinal microbiota, and the immune response. Inflammatory bowel diseases are systemic diseases that are not limited to the gastrointestinal tract and may affect many organ systems. Extraintestinal manifestations (EIM) most commonly affect the musculoskeletal system, skin, hepatobiliary tract, eyes, mucous membranes, and less commonly the lungs, pancreas, kidneys, nervous and cardiovascular systems. 50% of patients develop at least one EIM during their lifetime, sometimes even before diagnosis. Some EIM are directly related to the activity of the underlying disease (arthritis, aphthous stomatitis, nodular erythema, and episcleritis), some have an independent course (ankylosing spondylitis, uveitis), and some may or may not be associated with disease activity (primary sclerosing cholangitis, gangrenous pyoderma). The symptoms of EIM can be very debilitating. EIM that are related to activity of disease, optimal therapy for IBD with careful monitoring of the patient is often sufficient to relieve symptoms. EIM that are independent of disease activity may require a multidisciplinary team and additional therapy. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:783144
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-07-12 12:57:07
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