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master's thesis
Kliničke osobine bolesnika s akutnim zatajivanjem srca u vrijeme pandemije COVIDA-19
2021. urn:nbn:hr:184:952878
Pejić, Domagoj
University of Rijeka
Faculty of Medicine
Department of Internal Medicine

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Pejić, D. (2021). Kliničke osobine bolesnika s akutnim zatajivanjem srca u vrijeme pandemije COVIDA-19 (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:952878

Pejić, Domagoj. "Kliničke osobine bolesnika s akutnim zatajivanjem srca u vrijeme pandemije COVIDA-19." Master's thesis, University of Rijeka, Faculty of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:184:952878

Pejić, Domagoj. "Kliničke osobine bolesnika s akutnim zatajivanjem srca u vrijeme pandemije COVIDA-19." Master's thesis, University of Rijeka, Faculty of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:184:952878

Pejić, D. (2021). 'Kliničke osobine bolesnika s akutnim zatajivanjem srca u vrijeme pandemije COVIDA-19', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 05 December 2024, https://urn.nsk.hr/urn:nbn:hr:184:952878

Pejić D. Kliničke osobine bolesnika s akutnim zatajivanjem srca u vrijeme pandemije COVIDA-19 [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2021 [cited 2024 December 05] Available at: https://urn.nsk.hr/urn:nbn:hr:184:952878

D. Pejić, "Kliničke osobine bolesnika s akutnim zatajivanjem srca u vrijeme pandemije COVIDA-19", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:184:952878

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TitleKliničke osobine bolesnika s akutnim zatajivanjem srca u vrijeme pandemije COVIDA-19
Title (english)Clinical features in patients with acute heart failure during the COVID-19 pandemic.
AuthorDomagoj Pejić
MentorTeodora Zaninović Jurjević (mentor)
MentorŠtefica Dvornik (komentor)
Committee memberZlatko Čubranić (predsjednik povjerenstva)
Committee memberJagoda Ravlić-Gulan (član povjerenstva)
Committee memberVladimir Mićović (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Rijeka
Defense date and country2021-07-16, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Zatajivanje srca složeni je klinički sindrom koji je razlog sve većeg broja hospitalizacija i smrtnosti u razvijenom, zapadnom svijetu. Starija životna dob, brojni komorbiditeti i aktivna pandemija COVID-19 idu u prilog manjem broju hospitalizacija, težoj kliničkoj slici i povećanoj smrtnosti u razdoblju pandemije. Nastojeći utvrditi međusobnu povezanost, u razdoblju od 1.siječnja 2021. do 1. travnja 2021. analizirali smo povijest bolesti 133 bolesnika hospitaliziranih zbog ZS na Klinici za bolesti srca i krvnih žila KBC-a Rijeka te ih usporedili sa kliničkim značajkama bolesnika iz istog razdoblja 2019. godine. Usporedba kliničkih osobina pokazala je statistički značajne razlike u visini sistoličkog i dijastoličkog krvnog tlaka između dviju skupina bolesnika, više vrijednosti su mjerene u vrijeme pandemije. Također se pokazala statistički značajna razlika glede DM koji je kao komorbiditet bio učestaliji u bolesnika za vrijeme pandemije, te u perifernoj arterijskoj bolesti koja je kao komorbiditet više prevladavala u skupini bolesnika prije pandemije. Od laboratorijskih parametara naišlo se na statistički značajnu razliku u vrijednostima natrija između dvije skupine bolesnika, a više koncentracije natrija prevladavale su u skupini bolesnika hospitaliziranih za vrijeme pandemije. Naposlijetku, statistički značajna razlika vidljiva je u primjeni farmakološke terapije gdje su MRA, ARB, digitalis i antitrombotici statistički značajnije bili primjenjivani u bolesnika prije pandemije, dok su blokatori kalcijskih kanala statistički značajnije primjenjivani za vrijeme pandemije. Nije nađeno razlike u intrahospitalnoj smrtnosti (p=0,142) između dvije skupine bolesnika liječenih zbog ZS na Klinici za bolesti srca i krvnih žila u vrijeme i prije COVID-19 pandemije.
Abstract (english)
Heart failure is a complex clinical syndrome and is the reason for the ever increasing number of hospitalization and fatal outcomes in the world, especially in Western countries. Elderly age, numerous comorbidities and currently ongoing COVID-19 pandemic results in fewer hospitalizations, more severe clinical presentation and more deaths in times of pandemic. Trying to determine cause and consequence relations between different clinical parameters, in this research the clinical data of 133 patients were analized in the time interval between 1th of January 2021. and 1th of April 2021. and cross-referenced with the data from the same interval in 2019. Cross-referencing clinical data showed statistically significant difference in values of systolic and diastolic blood pressure between two groups with higher values being shown during the pandemic. Statistically significant difference can also be seen in diabetes which was, as a comobidity, more prevalent in group of patients hospitalized during the pandemic and in peripheral artery disease (PAD) which was more frequent before the pandemic. As for laboratory data, statistically significant difference was found in concentrations of sodium, and those values were higher during the pandemic. Lastly, statistically significant differences were found in usage of MRAs, ARBs, digitalis and antithrombotics which were used more frequently in patients before the pandemic, and calcium channel antagonists which were used more frequently during the pandemic. The study did not show any difference in the number of deaths between the two patient groups (p=0,142) hospitalized because of the heart failure in The Heart and vasculary diseases Clinic in the time of the pandemic and before.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:952878
ProjectNumber: UNIRI COVID projekt 2
Title: Psihološke promjene bolesnika s akutizacijom kroničnog zatajivanja srca tijekom COVID-19 epidemije
Title: Psychological changes in acutely decompensated heart failure patients during the COVID-19 epidemia
Leader: Teodora Zaninović Jurjević
Jurisdiction: Croatia
Funder: NadSve
Funding stream: Sveučilište u Rijeci
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-07-01 15:19:52