prikaz prve stranice dokumenta Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease
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Scientific paper - Original scientific paper
Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease
BMC Cardiovascular Disorders, 21 (2021), 1; 188. https://doi.org/10.1186/s12872-021-01959-x
Raljević, Damir; Peršić, Viktor; Markova-Car, Elitza; Cindrić, Leon; Miškulin, Rajko; Žuvić, Marta; Kraljević Pavelić, Sandra

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Raljević, D., Peršić, V., Markova Car, E., Cindrić, L., Miškulin, R., Žuvić, M. & Kraljević Pavelić, S. (2021). Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease. BMC Cardiovascular Disorders, 21. (1). doi: 10.1186/s12872-021-01959-x

Raljević, Damir, et al. "Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease." BMC Cardiovascular Disorders, vol. 21, no. 1, 2021. https://doi.org/10.1186/s12872-021-01959-x

Raljević, Damir, Viktor Peršić, Elitza Markova Car, Leon Cindrić, Rajko Miškulin, Marta Žuvić and Sandra Kraljević Pavelić. "Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease." BMC Cardiovascular Disorders 21, no. 1 (2021). https://doi.org/10.1186/s12872-021-01959-x

Raljević, D., et al. (2021) 'Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease', BMC Cardiovascular Disorders, 21(1). doi: 10.1186/s12872-021-01959-x

Raljević D, Peršić V, Markova Car E, Cindrić L, Miškulin R, Žuvić M, and sur.. Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease. BMC Cardiovascular Disorders [Internet]. 2021 April 16 [cited 2024 September 30];21(1). doi: 10.1186/s12872-021-01959-x

D. Raljević, et al., "Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease", BMC Cardiovascular Disorders, vol. 21, no. 1, April 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:293984. [Accessed: 30 September 2024]

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Metadata
Title (english)Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease
AuthorDamir Raljević
AuthorViktor Peršić
AuthorElitza Markova-Car
MBZ: 284336
AuthorLeon Cindrić
AuthorRajko Miškulin
AuthorMarta Žuvić
AuthorSandra Kraljević Pavelić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Rehabilitatiom Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Background: Vitamin D deficiency is associated with cardiovascular diseases, including coronary artery diseases (CAD). As vitamin D manifests its biological function through its vitamin D receptor (VDR), VDR gene polymorphisms potentially affect VDR functionality and vitamin D activity. Therefore, the objective of this study was to analyze three well-studied VDR gene polymorphisms- Fok1 (rs2228570), BsmI (rs1544410) and Taq1 (rs731236)-in a cohort of CAD patients after acute myocardial infarction. Methods: In the presented cross-sectional study, 155 participants with CAD after acute myocardial infarction and 104 participants in a control group without CAD were enrolled. The participants in both groups were Caucasians of European origin. The genotyping of VDR polymorphisms rs2228570, rs1544410 and rs731236 was assessed by RT-PCR. Results: The results show an association between the T/T genotype of the BsmI (rs1544410) and the G/G genotype of the Taq1 (rs731236) VDR polymorphism and CAD patients after acute myocardial infarction. There was no association between the Fok1 (rs2228570) VDR polymorphism and CAD patients after acute myocardial infarction. Conclusion: The presented results suggest a potential association of the BsmI (rs1544410) and Taq1 (rs731236) VDR polymorphisms with CAD patients after myocardial infarction.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBMC Cardiovascular Disorders
Numberingvol. 21, no. 1, 188
e-ISSN1471-2261
DOIhttps://doi.org/10.1186/s12872-021-01959-x
URN:NBNurn:nbn:hr:184:293984
Publication2021-04-16
ProjectNumber: uniri-biomed-18-257
Title (croatian): Cirlkadijalni geni u planocelularnog karcinoma larinksa
Title (english): Circadian genes in laryngeal squamous cell carcinoma
Leader: Elitza Petkova Markova-Car
Jurisdiction: Croatia
Funding stream: Sveučilište u Rijeci
Document URLhttps://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-021-01959-x
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2021-04-20 20:04:03