prikaz prve stranice dokumenta Purinergic receptor antagonism: A viable strategy for the management of autonomic dysreflexia?
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Scientific paper - Preliminary note / Short communication
Purinergic receptor antagonism: A viable strategy for the management of autonomic dysreflexia?
Autonomic Neuroscience, 230 (2021); 102741. https://doi.org/10.1016/j.autneu.2020.102741
Minić, Željka; O'Leary, Donal S.; Reynolds, Christian A.

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Minić, Ž., O'Leary, D. S. & Reynolds, C. A. (2021). Purinergic receptor antagonism: A viable strategy for the management of autonomic dysreflexia?. Autonomic Neuroscience, 230.. doi: 10.1016/j.autneu.2020.102741

Minić, Željka, et al. "Purinergic receptor antagonism: A viable strategy for the management of autonomic dysreflexia?." Autonomic Neuroscience, vol. 230, 2021. https://doi.org/10.1016/j.autneu.2020.102741

Minić, Željka, Donal S. O'Leary and Christian A. Reynolds. "Purinergic receptor antagonism: A viable strategy for the management of autonomic dysreflexia?." Autonomic Neuroscience 230 (2021). https://doi.org/10.1016/j.autneu.2020.102741

Minić, Ž., O'Leary, D. S. and Reynolds, C. A. (2021) 'Purinergic receptor antagonism: A viable strategy for the management of autonomic dysreflexia?', Autonomic Neuroscience, 230. doi: 10.1016/j.autneu.2020.102741

Minić Ž, O'Leary DS, Reynolds CA. Purinergic receptor antagonism: A viable strategy for the management of autonomic dysreflexia?. Autonomic Neuroscience [Internet]. 2021 January [cited 2024 December 26];230. doi: 10.1016/j.autneu.2020.102741

Ž. Minić, D. S. O'Leary and C. A. Reynolds, "Purinergic receptor antagonism: A viable strategy for the management of autonomic dysreflexia?", Autonomic Neuroscience, vol. 230, January 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:895210. [Accessed: 26 December 2024]

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Metadata
Title (english)Purinergic receptor antagonism: A viable strategy for the management of autonomic dysreflexia?
AuthorŽeljka Minić
AuthorDonal S. O'Leary
AuthorChristian A. Reynolds
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Physiology, Immunology and Pathophxsiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
The purinergic receptor ligand, ATP, may participate in reflex induced vasoconstriction through sympathetic efferent and sensory afferent mechanisms. However, the role of the purinergic system in contributing to autonomic dysreflexia following spinal cord injury is unclear. The present study investigates the involvement of P2X receptors in contributing to pressor responses during autonomic dysreflexia. Twenty rats were subjected to spinal cord injury and 24 h later hemodynamic responses to colorectal distension were recorded. Animals were randomized to receive intravenous administration of the P2X receptor antagonist, NF023, or vehicle control. The data indicate that NF023 attenuates pressor responses to colorectal distension.
Keywords (english)
Languageenglish
Publication typeScientific paper - Preliminary note / Short communication
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleAutonomic Neuroscience
Numberingvol. 230, 102741
p-ISSN1566-0702
DOIhttps://doi.org/10.1016/j.autneu.2020.102741
URN:NBNurn:nbn:hr:184:895210
Publication2021-01
Document URLhttps://linkinghub.elsevier.com/retrieve/pii/S1566070220301752
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2021-01-29 18:03:51