Salivary gland disorders can be divided into non-neoplastic and neoplastic group. Infectious diseases of salivary glands are classified as non-neoplastic. Etiological factors include bacteria, viruses and fungi. The most commonly affected are the parotid glands. One of the most important predisposing factor is decreased salivary flow, which can be caused by systemic diseases, use of some medicaments or because of the damage and necrosis of glandular tissue due to radiotherapy. The most common infective salivary gland disease is mumps, caused by Paramyxovirus. The incidence of mumps was drastically reduced since the implementation of vaccination using the combined rubella, mumps and measles vaccine. Aside from EP, viral sialadenitis can be caused by CMV, EBV, Coxackie virus type A, echovirus, influenza and parainfluenza viruses. The treatment is symptomatic. Bacterial infections can be subdivided into acute or chronic. Clinical features of acute suppurative sialadenitis include general symptoms, swelling of the affected gland and purulent exudation from the duct. Treatment includes the use of antibiotics and supportive therapy. Chronic recurrent sialadenitis mainly affects children, and usually resolves spontaneously after puberty. HIV-positive patients are more commonly affected with sialadenitis. Along with the salivary gland infection, the main disease should be treated. Parotid infections due to fungi are rare.