Epigenetički biomarkeri u presađivanju bubrega

Frančić, Klara; Katalinić, Nataša; Balen, Sanja

doi:10.21860/medflum2020_245225

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Scientific paper - Review paper

Epigenetički biomarkeri u presađivanju bubrega

Medicina Fluminensis : Medicina Fluminensis, 56 (2020), 4; 475-482. https://doi.org/10.21860/medflum2020_245225

Frančić, Klara; Katalinić, Nataša; Balen, Sanja

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APA 6th Edition

Frančić, K., Katalinić, N. & Balen, S. (2020). Epigenetički biomarkeri u presađivanju bubrega. Medicina Fluminensis : Medicina Fluminensis, 56. (4), 475-482. doi: 10.21860/medflum2020_245225

MLA 8th Edition

Frančić, Klara, et al. "Epigenetički biomarkeri u presađivanju bubrega." Medicina Fluminensis : Medicina Fluminensis, vol. 56, no. 4, 2020, pp. 475-482. https://doi.org/10.21860/medflum2020_245225

Chicago 17th Edition

Frančić, Klara, Nataša Katalinić and Sanja Balen. "Epigenetički biomarkeri u presađivanju bubrega." Medicina Fluminensis : Medicina Fluminensis 56, no. 4 (2020): 475-482. https://doi.org/10.21860/medflum2020_245225

Harvard

Frančić, K., Katalinić, N. and Balen, S. (2020) 'Epigenetički biomarkeri u presađivanju bubrega', Medicina Fluminensis : Medicina Fluminensis, 56(4), pp. 475-482. doi: 10.21860/medflum2020_245225

Vancouver

Frančić K, Katalinić N, Balen S. Epigenetički biomarkeri u presađivanju bubrega. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2020 [cited 2024 November 12];56(4):475-482. doi: 10.21860/medflum2020_245225

IEEE

K. Frančić, N. Katalinić and S. Balen, "Epigenetički biomarkeri u presađivanju bubrega", Medicina Fluminensis : Medicina Fluminensis, vol. 56, no. 4, pp. 475-482, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:965424. [Accessed: 12 November 2024]

Cite this item: https://urn.nsk.hr/urn:nbn:hr:184:965424

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Metadata

Title (croatian)	Epigenetički biomarkeri u presađivanju bubrega
Title (english)	Epigenetic biomarkers in kidney transplantation
Author	Klara Frančić
Author	Nataša Katalinić
Author	Sanja Balen MBZ: 236875
Author's institution	University of Rijeka Faculty of Medicine (Department of Clinical Laboratory Diagnostics)
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Urology
Abstract (croatian)	Križna proba, koncentracija kreatinina u serumu i procjena glomerularne filtracije, proteinurije te patohistološki nalaz biopsijom dobivenoga tkiva presatka biološki su markeri koji se koriste u transplantacijskoj medicini. Razvoj genetike i novih tehnologija omogućio je otkriće novih biomarkera kao ranih prediktora akutne reakcije odbacivanja, odgođene funkcije presatka, ishemijsko-reperfuzijske ozljede, intersticijske fibroze i atrofije tubula te dugoročnoga preživljavanja presatka. Radi boljega razumijevanja utjecaja okolišnih čimbenika na humani genom i njihove povezanosti s imunosnim odgovorom u presađivanju bubrega, provedena su brojna istraživanja o epigenetičkim mehanizmima. Cilj je rada prikazati potencijalne epigenetičke biomarkere, produkte epigenetičkih mehanizama i njihovu važnost u ishodu presađivanja bubrega.
Abstract (english)	Currently used prognostic biomarkers in kidney transplantation are – crossmatch, serum creatinine concentration and evaluation of glomerular filtration rate, proteinuria and a histopathological analysis of graft biopsy. The development of genetics and new technologies has enabled the discovery of new biomarkers as early predictors of acute rejection response, delayed graft function, ischemia-reperfusion injury, interstitial fibrosis, tubular atrophy and long-term graft survival. Numerous studies have been conducted to examine the influence of environmental factors on human genome and its relation with the immune response in kidney transplantation. The aim of this article is to present potential epigenetic biomarkers – the products of epigenetic mechanisms, and their importance in the outcome of renal transplantation.
Keywords (croatian)
Keywords (english)
Language	croatian
Language	english
Publication type	Scientific paper - Review paper
Publication status	Published
Peer review	Peer review
Publication version	Published version
Journal title	Medicina Fluminensis : Medicina Fluminensis
Numbering	vol. 56, no. 4, pp. 475-482
p-ISSN	1847-6864
e-ISSN	1848-820X
DOI	https://doi.org/10.21860/medflum2020_245225
URN:NBN	urn:nbn:hr:184:965424
Publication	2020
Document URL	https://hrcak.srce.hr/245225
Type of resource	Text
Access conditions	Open access
Terms of use
Created on	2020-12-01 10:31:31