prikaz prve stranice dokumenta Acute antibody-mediated rejection of the kidney transplant – experience of a single center in Croatia
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Scientific paper - Original scientific paper
Acute antibody-mediated rejection of the kidney transplant – experience of a single center in Croatia
Medicinski Glasnik, 11 (2013), 1; 138-144. urn:nbn:hr:184:948533
Orlić, Lidija; Sladoje-Martinović, Branka; Mikolašević, Ivana; Pavletić Peršić, Martina; Bubić, Ivan; Jelić, Ita; Rački, Sanjin

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Orlić, L., Sladoje Martinović, B., Mikolašević, I., Pavletić Peršić, M., Bubić, I., Jelić, I. & Rački, S. (2013). Acute antibody-mediated rejection of the kidney transplant – experience of a single center in Croatia. Medicinski Glasnik, 11. (1), 138-144. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:948533

Orlić, Lidija, et al. "Acute antibody-mediated rejection of the kidney transplant – experience of a single center in Croatia." Medicinski Glasnik, vol. 11, no. 1, 2013, pp. 138-144. https://urn.nsk.hr/urn:nbn:hr:184:948533

Orlić, Lidija, Branka Sladoje Martinović, Ivana Mikolašević, Martina Pavletić Peršić, Ivan Bubić, Ita Jelić and Sanjin Rački. "Acute antibody-mediated rejection of the kidney transplant – experience of a single center in Croatia." Medicinski Glasnik 11, no. 1 (2013): 138-144. https://urn.nsk.hr/urn:nbn:hr:184:948533

Orlić, L., et al. (2013) 'Acute antibody-mediated rejection of the kidney transplant – experience of a single center in Croatia', Medicinski Glasnik, 11(1), pp. 138-144. Available at: https://urn.nsk.hr/urn:nbn:hr:184:948533 (Accessed 24 December 2024)

Orlić L, Sladoje Martinović B, Mikolašević I, Pavletić Peršić M, Bubić I, Jelić I, and sur.. Acute antibody-mediated rejection of the kidney transplant – experience of a single center in Croatia. Medicinski Glasnik [Internet]. 2013 [cited 2024 December 24];11(1):138-144. Available at: https://urn.nsk.hr/urn:nbn:hr:184:948533

L. Orlić, et al., "Acute antibody-mediated rejection of the kidney transplant – experience of a single center in Croatia", Medicinski Glasnik, vol. 11, no. 1, pp. 138-144, 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:948533. [Accessed: 24 December 2024]

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Metadata
Title (english)Acute antibody-mediated rejection of the kidney transplant – experience of a single center in Croatia
AuthorLidija Orlić
AuthorBranka Sladoje-Martinović
AuthorIvana Mikolašević
AuthorMartina Pavletić Peršić
AuthorIvan Bubić
AuthorIta Jelić
AuthorSanjin Rački
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Aim To describe the experience of the Department of Nephrology and Dialysis, University Hospital Rijeka, Croatia, in the treatment of patients with acute humoral rejection (AHR) of kidney transplant by using high dose of intravenous immunoglobulin (IVIG) alone and as a first line treatment. Methods Eight kidney transplant recipients in whom the AHR appeared at different time after the transplantation were reported. At the time of transplantation cross-match in all patients was negative for both T and B cells. At the time of presentation, all patients had signs of renal allograft dysfunction and the rejection was proven by biopsy of the kidney transplant with positive C4d-staining and histopathological evidence of antibody-mediated injury. Early rejection was considered within 180 days after the transplantation and the late one 180 days after the transplantation. In two cases plasmapheresis (PAF) with albumin as replacement fluid was performed. Plasma exchange was done with a 35 mL/kg/body weight volume exchange with albumin for six times. Results Acute humoral rejection was classified as early in three patients and in five as late one. In two patients PAF had been performed as the first line treatment. After the completion of PAF, recuperation of severe graft dysfunction was incomplete and in addition IVIG (as a single dose of 2.0 g/kg) was administered to these patients. In six patients IVIG as a single dose of 2.0 g/kg was applied as the first line treatment. Conclusion Usage of high dose IVIG in the treatment of the acute humoral rejection is efficient, safe and relatively well tolerated
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleMedicinski Glasnik
Numberingvol. 11, no. 1, pp. 138-144
p-ISSN1840-0132
URN:NBNurn:nbn:hr:184:948533
Publication2013
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) icon
Created on2020-11-25 14:39:42