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The Role of Lymphadenectomy in Prostate Cancer Patients
Acta clinica Croatica, 58 (2019), Supplement 2; 24-35. https://doi.org/10.20471/acc.2019.58.s2.05
Markić, Dean; Oguić, Romano; Krpina, Kristian; Vukelić, Ivan; Đorđević, Gordana; Žuža, Iva; Josip Španjol, Josip

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Markić, D., Oguić, R., Krpina, K., Vukelić, I., Đorđević, G., Žuža, I. & Josip Španjol, J. (2019). The Role of Lymphadenectomy in Prostate Cancer Patients. Acta clinica Croatica, 58. (Supplement 2), 24-35. doi: 10.20471/acc.2019.58.s2.05

Markić, Dean, et al. "The Role of Lymphadenectomy in Prostate Cancer Patients." Acta clinica Croatica, vol. 58, no. Supplement 2, 2019, pp. 24-35. https://doi.org/10.20471/acc.2019.58.s2.05

Markić, Dean, Romano Oguić, Kristian Krpina, Ivan Vukelić, Gordana Đorđević, Iva Žuža and Josip Josip Španjol. "The Role of Lymphadenectomy in Prostate Cancer Patients." Acta clinica Croatica 58, no. Supplement 2 (2019): 24-35. https://doi.org/10.20471/acc.2019.58.s2.05

Markić, D., et al. (2019) 'The Role of Lymphadenectomy in Prostate Cancer Patients', Acta clinica Croatica, 58(Supplement 2), pp. 24-35. doi: 10.20471/acc.2019.58.s2.05

Markić D, Oguić R, Krpina K, Vukelić I, Đorđević G, Žuža I, and sur.. The Role of Lymphadenectomy in Prostate Cancer Patients. Acta clinica Croatica [Internet]. 2019 [cited 2024 December 05];58(Supplement 2):24-35. doi: 10.20471/acc.2019.58.s2.05

D. Markić, et al., "The Role of Lymphadenectomy in Prostate Cancer Patients", Acta clinica Croatica, vol. 58, no. Supplement 2, pp. 24-35, 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:787588. [Accessed: 05 December 2024]

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Metadata
Title (english)The Role of Lymphadenectomy in Prostate Cancer Patients
Title (croatian)Uloga limfadenektomije u bolesnika s karcinomom prostate
AuthorDean Markić
AuthorRomano Oguić
AuthorKristian Krpina
AuthorIvan Vukelić
AuthorGordana Đorđević
AuthorIva Žuža
AuthorJosip Josip Španjol
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of General Pathology and Pathological Anatomy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Urology
Abstract (english)
Prostate cancer is one of the most important men’s health issues in developed countries. For patients with prostate cancer a preoperative staging of the disease must be made. Involvement of lymph nodes could be assessed using imaging methods (CT or/and MRI), however, newer methods also exist (PET/CT, PSMA PET/CT). For some patients during radical prostatectomy a pelvic lymphadenectomy is recommended. Pelvic lymphadenectomy is indicated in intermediate- and high-risk group patients and with increased probability of lymph node invasion. The most used prediction tools for preoperative assessment of lymph nodes are Briganti and MSKCC nomograms and Partin tables. Pelvic lymphadenectomy can include different lymph nodes group, but extended lymphadenectomy is the recommended procedure. In 1-20% of patients, the lymph node invasion is present. Pelvic lymphadenectomy is primarily a diagnostic and staging method, and in minority of patients with positive lymph nodes it can be a curative method, too. In other patients with positive lymph nodes adjuvant therapy (radiotherapy and androgen deprivation therapy) can be beneficial.
Abstract (croatian)
Karcinom prostate je jedan od značajnijih zdravstvenih problema muškaraca u razvijenom dijelu svijeta. U bolesnika s dijagnosticiranim karcinomom prostate neophodno je učiniti prijeoperacijsko stupnjevanje bolesti. Zahvaćenost limfnih čvorova se standardno određuje uz pomoć slikovnih metoda (CT i/ili/ MR) iako postoje i novije metode (PET/CT, PSMA PET/CT). U određenog broja bolesnika prilikom radikalne prostatektomije treba učiniti i zdjeličnu limfadenektomiju. Odluka o potrebi za zdjeličnom limfadenektomijom se donosi na osnovu svrstavanja bolesnika u umjerenu odnosno grupu visokoga rizika i ako je vjerojatnost za zahvaćenost limfnih čvorova povećana. Najčešće danas korišteni nomogrami za prijeoperacijsku procjenu zahvaćenosti limfnih čvorova su Briganti i MSKCC nomogram te Partinove tablice. Zdjelična limfadenektomija može obuhvaćati različite skupine limfnih čvorova ali se preporuča učiniti proširenu zdjeličnu limfadenektomiju. U 1-20% bolesnika nalaze se pozitivni limfni čvorovi. Iako zdjelična limfadenektomija ima prvenstveno dijagnostički i prognostički značaj, u manjeg broja bolesnika s pozitivnim limfnim čvorovima može biti i definitivna terapijska metoda. U ostalih bolesnika s pozitivnim limfnim čvorovima adjuvantna terapija (radioterapija i androgen deprivacijska terapija) može biti od terapijskog značaja.
Keywords (english)
Keywords (croatian)
Languageenglish
Languagecroatian
Publication typeProfessional paper - Professional paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 58, no. Supplement 2, pp. 24-35
p-ISSN0353-9466
e-ISSN1333-9451
DOIhttps://doi.org/10.20471/acc.2019.58.s2.05
URN:NBNurn:nbn:hr:184:787588
Publication2019
Document URLhttps://hrcak.srce.hr/234258
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) icon
Created on2020-02-18 11:04:01