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master's thesis
KUTANI ERITEMSKI LUPUS - KLASIFIKACIJA I KLINIČKO-PATOLOŠKA KORELACIJA
2019. urn:nbn:hr:184:541252
Marin, Kristina
University of Rijeka
Faculty of Medicine
Department of Dermatovenerology

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Marin, K. (2019). KUTANI ERITEMSKI LUPUS - KLASIFIKACIJA I KLINIČKO-PATOLOŠKA KORELACIJA (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:541252

Marin, Kristina. "KUTANI ERITEMSKI LUPUS - KLASIFIKACIJA I KLINIČKO-PATOLOŠKA KORELACIJA." Master's thesis, University of Rijeka, Faculty of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:184:541252

Marin, Kristina. "KUTANI ERITEMSKI LUPUS - KLASIFIKACIJA I KLINIČKO-PATOLOŠKA KORELACIJA." Master's thesis, University of Rijeka, Faculty of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:184:541252

Marin, K. (2019). 'KUTANI ERITEMSKI LUPUS - KLASIFIKACIJA I KLINIČKO-PATOLOŠKA KORELACIJA', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 31 December 2024, https://urn.nsk.hr/urn:nbn:hr:184:541252

Marin K. KUTANI ERITEMSKI LUPUS - KLASIFIKACIJA I KLINIČKO-PATOLOŠKA KORELACIJA [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2019 [cited 2024 December 31] Available at: https://urn.nsk.hr/urn:nbn:hr:184:541252

K. Marin, "KUTANI ERITEMSKI LUPUS - KLASIFIKACIJA I KLINIČKO-PATOLOŠKA KORELACIJA", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:184:541252

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Metadata
TitleKUTANI ERITEMSKI LUPUS - KLASIFIKACIJA I KLINIČKO-PATOLOŠKA KORELACIJA
Title (english)CUTANEOUS LUPUS ERYTHEMATOSUS - CLASSIFICATION AND CLINICO-PATHOLOGIC CORRELATION
AuthorKristina Marin
MentorSandra Peternel (mentor)
Committee memberMarija Kaštelan (predsjednik povjerenstva)
Committee memberSrđan Novak (član povjerenstva)
Committee memberInes Brajac (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Dermatovenerology)
Rijeka
Defense date and country2019-07-12, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Dermatovenerology
Abstract
Kutani eritemski lupus (CLE) obuhvaća širok spektar dermatoloških manifestacija, koje mogu ili ne moraju biti povezane s razvojem sistemne bolesti. Točan uzrok bolesti je nepoznat, ali se smatra da je bolest autoimune prirode te da veliku ulogu igraju genetički čimbenici i okolišni faktori. Danas je prihvaćena „Düsseldorfska klasifikacija“ bolesti . Prema njoj se CLE dijeli na akutni (ACLE), subakutni (SCLE), kronični (CCLE) te intermitentni (ICLE) oblik bolesti. Dijagnoza se postavlja na temelju kliničke slike, patohistološke i direktne imunofluorescentne pretrage bioptata kože, laboratorijskih i seroloških nalaza. Histopatološki, za svaki oblik CLE-a se mogu naći specifične promjene, no promjene poput interface dermatitisa i abnormalnih nakupina dermalnog mucina su vidljive u gotovo svim oblicima CLE-a. Liječenje kožnog lupusa sastoji se od edukacije pacijenata o pravilnoj zaštiti od sunca zajedno s odgovarajućom topičkom i sustavnom terapijom.
Abstract (english)
Cutaneous lupus erythematosus (CLE) encompasses a wide range of dermatologic manifestations, which may or may not be associated with the development of systemic disease. The exact cause of the disease is unknown, but it is thought to be an autoimmune disease, while genetic and environmental factors play a major role. Current CLE classification is the "Düsseldorf Classification", according to which CLE is divided into acute (ACLE), subacutE (SCLE), chronic (CCLE), and a newly defined er intermittent (ICLE) subtype. Diagnosis is based on clinical presentation, histopathological findings of skin biopsy, direct immunofluorescence, laboratory and serological findings. Histopathologically, specific changes may be found for each CLE subtype, but alterations such as interface dermatitis and accumulation of dermal mucin are visible in almost all CLE forms. Treatment of cutaneous lupus consists of patient education on proper sun protection along with appropriate topical and systemic therapy
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:541252
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-01-22 08:36:55