prikaz prve stranice dokumenta Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease Proven by Transient Elastography
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Scientific paper - Original scientific paper
Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease Proven by Transient Elastography
Kidney and Blood Pressure Research, 37 (2013), 4-5; 305-310. https://doi.org/10.1159/000350158
Mikolašević, Ivana; Rački, Sanjin; Bubić, Ivan; Jelić, Ita; Štimac, Davor; Orlić, Lidija

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Mikolašević, I., Rački, S., Bubić, I., Jelić, I., Štimac, D. & Orlić, L. (2013). Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease Proven by Transient Elastography. Kidney and Blood Pressure Research, 37. (4-5), 305-310. doi: 10.1159/000350158

Mikolašević, Ivana, et al. "Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease Proven by Transient Elastography." Kidney and Blood Pressure Research, vol. 37, no. 4-5, 2013, pp. 305-310. https://doi.org/10.1159/000350158

Mikolašević, Ivana, Sanjin Rački, Ivan Bubić, Ita Jelić, Davor Štimac and Lidija Orlić. "Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease Proven by Transient Elastography." Kidney and Blood Pressure Research 37, no. 4-5 (2013): 305-310. https://doi.org/10.1159/000350158

Mikolašević, I., et al. (2013) 'Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease Proven by Transient Elastography', Kidney and Blood Pressure Research, 37(4-5), pp. 305-310. doi: 10.1159/000350158

Mikolašević I, Rački S, Bubić I, Jelić I, Štimac D, Orlić L. Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease Proven by Transient Elastography. Kidney and Blood Pressure Research [Internet]. 2013 [cited 2024 November 15];37(4-5):305-310. doi: 10.1159/000350158

I. Mikolašević, S. Rački, I. Bubić, I. Jelić, D. Štimac and L. Orlić, "Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease Proven by Transient Elastography", Kidney and Blood Pressure Research, vol. 37, no. 4-5, pp. 305-310, 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:840298. [Accessed: 15 November 2024]

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Metadata
Title (english)Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease Proven by Transient Elastography
AuthorIvana Mikolašević
AuthorSanjin Rački
AuthorIvan Bubić
AuthorIta Jelić
AuthorDavor Štimac
AuthorLidija Orlić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Urology
Abstract (english)
Background/Aim: Preliminary data suggest an association between chronic kidney disease (CKD) and non-alcoholic fatty liver disease (NAFLD). The aim of this study was to further investigate the association between NAFLD and decreased kidney function. Methods: A total of 62 patients with CKD were enrolled in the study. Liver stiffness was used to detect liver fibrosis and CAP (controlled attenuation parameter) was used to detect and quantify liver steatosis (Fibroscan®). NAFLD was defined by CAP values ≥238 dB.m-1. Results: CKD stage III was present in 29 patients (46.8%) and CKD stage IV in 33 patients (53.2%). Out of 62 CKD patients 53 (85.5%) had NAFLD and of these 14/53 patients (26.4%) had also liver stiffness >7 kPa. The severity of liver steatosis was positively correlated with serum creatinine (r=0.399;p<0.01) and CRP (r=0.261; p<0.05) and negatively correlated with eGFR (r=-0.413; p<0.01) and serum iron concentration (r=-0.365; p<0.01). Conclusion: The results suggest a high prevalence of NAFLD in CKD patients. The severity of liver steatosis is negatively correlated with kidney function. The study documents the value of ultrasonographic elastography as an effective non-invasive screening method for the diagnosis of NAFLD.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleKidney and Blood Pressure Research
Numberingvol. 37, no. 4-5, pp. 305-310
p-ISSN1420-4096
e-ISSN1423-0143
DOIhttps://doi.org/10.1159/000350158
URN:NBNurn:nbn:hr:184:840298
Publication2013
Document URLhttps://www.karger.com/Article/FullText/350158
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0) icon
Created on2019-04-11 19:44:48