prikaz prve stranice dokumenta Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split
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Scientific paper - Original scientific paper
Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split
Medical Science Monitor, 17 (2011), 7; CR355-CR361. https://doi.org/10.12659/MSM.881845
Ilić, Tanja; Gračan, Sanda; Arapović, Adela; Čapkun, Vesna; Šubat-Dežulović, Mirna; Saraga, Marijan

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Ilić, T., Gračan, S., Arapović, A., Čapkun, V., Šubat Dežulović, M. & Saraga, M. (2011). Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split. Medical Science Monitor, 17. (7), CR355-CR361. doi: 10.12659/MSM.881845

Ilić, Tanja, et al. "Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split." Medical Science Monitor, vol. 17, no. 7, 2011, pp. CR355-CR361. https://doi.org/10.12659/MSM.881845

Ilić, Tanja, Sanda Gračan, Adela Arapović, Vesna Čapkun, Mirna Šubat Dežulović and Marijan Saraga. "Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split." Medical Science Monitor 17, no. 7 (2011): CR355-CR361. https://doi.org/10.12659/MSM.881845

Ilić, T., et al. (2011) 'Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split', Medical Science Monitor, 17(7), pp. CR355-CR361. doi: 10.12659/MSM.881845

Ilić T, Gračan S, Arapović A, Čapkun V, Šubat Dežulović M, Saraga M. Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split. Medical Science Monitor [Internet]. 2011 [cited 2024 November 13];17(7):CR355-CR361. doi: 10.12659/MSM.881845

T. Ilić, S. Gračan, A. Arapović, V. Čapkun, M. Šubat Dežulović and M. Saraga, "Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split", Medical Science Monitor, vol. 17, no. 7, pp. CR355-CR361, 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:971338. [Accessed: 13 November 2024]

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Metadata
Title (english)Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split
AuthorTanja Ilić
AuthorSanda Gračan
AuthorAdela Arapović
AuthorVesna Čapkun
AuthorMirna Šubat-Dežulović
AuthorMarijan Saraga
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Pediatrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Abstract (english)
Background: We assessed prevalence and resistance of uropathogens on antimicrobial agents (AA) from urine cultures (UC) in children hospitalized with urinary tract infections (UTI) at University Hospital in Split. Material/Methods: During the 7-year period, children hospitalized only once with UTI alone were compared to those repeatedly hospitalized, and who received long-term antimicrobial prophylaxis (LTAP), as well as those with associated anomalies of the urinary system (US). Results: E. coli was the most frequent isolate (67.7%) with resistance to ampicillin by 69.5%, amoxicillin/clavulonic acid by 3.5%, cephalexin by 6.6%, trimethoprim/sulfamethoxazole (TMP-SMX) by 27.5%, and nitrofurantoin by 0.4%. For other uropathogens, AA resistance rates were the following: 64.3%, 5.8%, 10.5%, 21.3%, and 7.9%. The high or increasing resistance to TMP-SMX is characterized by all uropathogens. Patients with anomalies of US showed a lower prevalence of E. coli and Enterococcus sp., but a higher prevalence of Pseudomonas sp., ESBL-producing E. coli and Klebsiella sp. than those without US anomalies. Repeatedly hospitalized patients showed a lower prevalence of E. coli, but a higher prevalence of Pseudomonas sp. and Klebsiella sp. than patients hospitalized only once. Both groups displayed significantly less resistance of Enterococcus sp. In patients receiving LTAP before hospitalization, E. coli was significantly more resistant to ampicillin, amoxicillin/clavulonic acid and TMP/SMX than in those without LTAP. Conclusions: Based on our results, we recommend excluding ampicillin altogether, and reconsideration of further use of TMP-SMX, as well as use of nitrofurantoin, cephalexin and amoxicillin/clavulonic acid for LTAP in our region.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleMedical Science Monitor
Numberingvol. 17, no. 7, pp. CR355-CR361
p-ISSN1234-1010
DOIhttps://doi.org/10.12659/MSM.881845
URN:NBNurn:nbn:hr:184:971338
Publication2011
Document URLhttp://www.medscimonit.com/abstract/index/idArt/881845
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2019-04-02 06:35:39