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Preemptivna transplantacija bubrega od živog darivatelja
Medica Jadertina, 46 (2016), 1-2; 43-46. urn:nbn:hr:184:682113
Markić, Dean; Španjol, Josip; Krpina, Kristian; Gršković, Antun; Rahelić, Dražen; Materljan, Mauro; Trošelj, Marin; Pavletić Peršić, Martina; Orlić, Lidija; Bubić, Ivan; Arefijev, Andrea; Rački, Sanjin

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Markić, D., Španjol, J., Krpina, K., Gršković, A., Rahelić, D., Materljan, M. ... Rački, S. (2016). Preemptivna transplantacija bubrega od živog darivatelja. Medica Jadertina, 46. (1-2), 43-46. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:682113

Markić, Dean, et al. "Preemptivna transplantacija bubrega od živog darivatelja." Medica Jadertina, vol. 46, no. 1-2, 2016, pp. 43-46. https://urn.nsk.hr/urn:nbn:hr:184:682113

Markić, Dean, Josip Španjol, Kristian Krpina, Antun Gršković, Dražen Rahelić, Mauro Materljan, Marin Trošelj, et al. "Preemptivna transplantacija bubrega od živog darivatelja." Medica Jadertina 46, no. 1-2 (2016): 43-46. https://urn.nsk.hr/urn:nbn:hr:184:682113

Markić, D., et al. (2016) 'Preemptivna transplantacija bubrega od živog darivatelja', Medica Jadertina, 46(1-2), pp. 43-46. Available at: https://urn.nsk.hr/urn:nbn:hr:184:682113 (Accessed 10 December 2024)

Markić D, Španjol J, Krpina K, Gršković A, Rahelić D, Materljan M, and sur.. Preemptivna transplantacija bubrega od živog darivatelja. Medica Jadertina [Internet]. 2016 [cited 2024 December 10];46(1-2):43-46. Available at: https://urn.nsk.hr/urn:nbn:hr:184:682113

D. Markić, et al., "Preemptivna transplantacija bubrega od živog darivatelja", Medica Jadertina, vol. 46, no. 1-2, pp. 43-46, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:682113. [Accessed: 10 December 2024]

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Metadata
Title (croatian)Preemptivna transplantacija bubrega od živog darivatelja
Title (english)Preemptive kidney transplantation from living donor
AuthorDean Markić
AuthorJosip Španjol
AuthorKristian Krpina
AuthorAntun Gršković
AuthorDražen Rahelić
AuthorMauro Materljan
AuthorMarin Trošelj
AuthorMartina Pavletić Peršić
AuthorLidija Orlić
AuthorIvan Bubić
AuthorAndrea Arefijev
AuthorSanjin Rački
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (croatian)
Preemptivna transplantacija bubrega je vrsta transplantacije koja se radi prije početka dijalitičkog liječenja. Ona omogućuje bolju kvalitetu života i značajno smanjenje troškova liječenja u odnosu na dijalizu, a također je uz nju vezano bolje preživljenje, kako presatka, tako i bolesnika. Prikazali smo 26-godišnjeg bolesnika koji ima kroničnu bubrežnu bolest (KBB) uzrokovanu IgA nefropatijom. Bubrežna funkcija bolesnika je unatoč primijenjenoj imunosupresivnoj terapiji postupno slabila tijekom vremena, ali je jedan napadaj akutnog enterokolitisa doveo do značajnog i trajnog slabljenja bubrežne funkcije. Kod bolesnika se tada počelo razmišljati o nadomještanju bubrežne funkcije. Bolesnikova majka je prihvaćena kao živi darivatelj. Lijevi bubreg majke je transplantiran u desnu ilijačnu jamu. Operacija i rani postoperacijski tijek prošli su bez komplikacija. Postoperacijski, a kao indukcijska terapija, koristila su se monoklonska protutijela protiv interleukina 2 sa standardnom trojnom imunosupresivnom terapijom koja se sastojala od kortikosteroida, mikofenolat-mofetila i takrolimusa. Godinu dana nakon transplantacije bolesnik ima dobro funkcionirajući presadak bez ikakvih kirurških ili imunoloških komplikacija. Zaključno može se reći da je preemptivna transplantacija bubrega efikasna metoda liječenja pacijenta s kroničnim bubrežnim zatajenjem i treba biti preporučena u svih bolesnika u kojih se može učiniti transplantacija.
Abstract (english)
Pre-emptive kidney transplantation is the type of transplantation that is performed before starting dialysis. It allows a better quality of life to the patient and significant reduction of costs in comparison with dialysis, and also is connected with higher survival rate of graft and patient. We present a 26-year-old patient diagnosed with chronic kidney disease (CKD) due to IgA nephropathy. His kidney function, despite of immunosuppressive therapy, gradually decreased in time but an onset of acute enterocolitis has lead to significant and permanent deterioration of kidney function with the forthcoming need for renal replacement therapy. His mother was accepted as a living kidney donor. The left kidney of the mother was transplanted to the right iliac fossa of the patient. The operation went without any complications. The postoperative course was uneventful with induction therapy with monoclonal antibody against interleukin 2 receptor and standard triple immunosuppressive therapy consisting of corticosteroid, mycophenolat mofetil and tacrolimus. One year after the transplantation, the patient has a good functioning kidney transplant without any surgical or immunological complications. Conclusively, pre-emptive kidney transplantation is an effective treatment for patients with end-stage renal disease and it should be recommended to all patients where this type of treatment is possible.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeProfessional paper - Professional paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedica Jadertina
Numberingvol. 46, no. 1-2, pp. 43-46
p-ISSN0351-0093
URN:NBNurn:nbn:hr:184:682113
Publication2016
Document URLhttps://hrcak.srce.hr/159883
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2019-03-13 17:18:38