Tetanus or „bad spasm“ is a disease caused by the bacterium of Clostridium tetani which is found in the intestinal microflora of animal who are also the main source of infection. Tetanus is a disease that belongs to zoonoses, and the infection is due to the occurrence of a tetanus sporadic disease in the affected wound. Spores of tetanus due to our environment by feces of a domestic animals and they are very resistant to outdoor conditions so they can survive for a long time. To cause the disease, tetanus spores have to come to the point of injury in the contaminated material which contains spores of tetanus, and the most often is that with a ground or the objects that were in touch with the ground. The disease begins to evolve ate the time when aerobic bacterias spend all oxygen and then create an anaerobic conditions in the wound where the spores of tetanus are changing in vegetative form and secreted exotoxin apropos neurotoxin. All clinical manifestations of the disease are caused by the neurotoxin that enters in the peripheral motor nerves, and they comes to the central nervous system to prevent the release of regulatory neuroprieversis which are result of tonique spasms or stiffness. Depending on the amount of toxins they can cause localized tetanus or generalized tetanus. In the Republic of Croatia, in the period from 2004 to 2016, the total number of people who was suffering from tetanus disease was 42, of which deaths were at 5 people. In 2016 the inoculation coverage stood at 80,4% for all age groups, the largest vaccination coverage was in Šibensko-kninska county (96,1%), while the lowest vaccination coverage was in Dubrovačko-neretvanska county (64,3%). For primary immunization in the period from 2004 to 2016, is a slight decrease in vaccine rate of 2,8%, while is secundary immunization decreased by 5,5% in the period of 2014 to 2016. The largest drop trend in the period between 2004 and 2016 was for vaccination of sixty year old people is 26,6%, while their averaged vaccination coverage is 61,2% and their are the most risk group to suffered from tetanus .