prikaz prve stranice dokumenta PANKREATITIS NAKON ENDOSKOPSKE RETROGRADNE KOLAGIOPANKREATOGRAFIJE
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master's thesis
PANKREATITIS NAKON ENDOSKOPSKE RETROGRADNE KOLAGIOPANKREATOGRAFIJE
2018. urn:nbn:hr:184:081052
Zović, Ivan
University of Rijeka
Faculty of Medicine
Department of Internal Medicine

Cite this document

Zović, I. (2018). PANKREATITIS NAKON ENDOSKOPSKE RETROGRADNE KOLAGIOPANKREATOGRAFIJE (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:081052

Zović, Ivan. "PANKREATITIS NAKON ENDOSKOPSKE RETROGRADNE KOLAGIOPANKREATOGRAFIJE." Master's thesis, University of Rijeka, Faculty of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:184:081052

Zović, Ivan. "PANKREATITIS NAKON ENDOSKOPSKE RETROGRADNE KOLAGIOPANKREATOGRAFIJE." Master's thesis, University of Rijeka, Faculty of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:184:081052

Zović, I. (2018). 'PANKREATITIS NAKON ENDOSKOPSKE RETROGRADNE KOLAGIOPANKREATOGRAFIJE', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 11 April 2025, https://urn.nsk.hr/urn:nbn:hr:184:081052

Zović I. PANKREATITIS NAKON ENDOSKOPSKE RETROGRADNE KOLAGIOPANKREATOGRAFIJE [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2018 [cited 2025 April 11] Available at: https://urn.nsk.hr/urn:nbn:hr:184:081052

I. Zović, "PANKREATITIS NAKON ENDOSKOPSKE RETROGRADNE KOLAGIOPANKREATOGRAFIJE", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:184:081052

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Metadata
TitlePANKREATITIS NAKON ENDOSKOPSKE RETROGRADNE KOLAGIOPANKREATOGRAFIJE
Title (english)PANCREATITS FOLLOWING ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY
AuthorIvan Zović
MentorVanja Licul (mentor)
Committee memberGoran Hauser (predsjednik povjerenstva)
Committee memberGoran Poropat (član povjerenstva)
Committee memberNada Starčević-Čizmarević (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Rijeka
Defense date and country2018-07-13, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Endoskopska retrogradna kolangiopankreatografija (ERCP) je tehnika koja kombinira fluoroskopiju i endoskopiju za dijagnozu i liječenje bolesti gušterače i žučnih kanala poput kamenaca, striktura i tumora. Najčešća komplikacija postupka je akutni pankreatitis koji se pojavljuje u 2-10% pacijenata podvrgnutih tom postupku. Smatra se da upala gušterače nastaje kao posljedica hidrostatske lezije i aktivacije enzima. Rezultat te aktivacije je razgradnja tkiva gušterače, ali i okolnih struktura. Bol... More je glavni klinički simptom; lokalizirana je u epigastriju i obično se širi u leđa praćena mučninom i povraćanjem. Pacijent je anksiozan te obično hipotenzivan i tahikardan. U vrijednostima biokemije se nalazi trostruko ili više povećanje vrijednosti serumskih lipaza i amilaza. Terapija je prvenstveno usmjerena na agresivnu hidraciju i smanjenje boli. Post-ERCP pankreatitis obično razvija blagi oblik bolesti koji je samoograničavajući i prolazi kroz tjedan dana. Kako bi se spriječio razvoj upale gušterače nakon ERCP-a isprobavane su brojne profilaktičke mjere, prvenstveno farmakološke. Lijekovi koji su se istraživali uključuju kortikosteroide, somatostatin, NSAID, alopurinol, ali pokušavane su i nefarmakološke mjere poput stentiranja kanala gušterače. Pozitivni rezultati studija koje su proučavale utjecaj indometacina i diklofenaka te utjecaj stentiranja pankreasnog kanala rezultirala su time da je Europsko gastroenterološko društvo te dvije metode izdvojilo kao preporuke u svojim smjernicama. Less
Abstract (english)
Endoscopic Retrograde Collangiopancreatography (ERCP) is a technique that combines fluoroscopy and endoscopy for the diagnosis and treatment of pancreatic and gastrointestinal diseases such are stones, strictures and tumors. The most common complication of the procedure is acute pancreatitis that occurs in 2-10% of patients undergoing the procedure. It is thought that the inflammation of the pancreas is the result of hydrostatic lesion and enzyme activation. The result of this activation is... More the decomposition of the pancreatic tissue and surrounding structures. Pain is the main clinical symptom, localized in the epigastrium and usually spreads to the back accompanied by nausea and vomiting. The patient is anxious and usually hypotensive and tachycardic. Post-ERCP pancratitis is charactarized by a triple increase in serum lipase and amylase levels. The therapy is primarily focused on aggressive hydration and pain reduction. Post-ERCP pancreatitis usually develops a mild form of disease that is self-limiting and resolves through 7 -10 days. In order to prevent the development of pancreatic inflammation after ERCP a number of prophylactic measures, primarily pharmacological, were tested. The drugs that were studied included corticosteroids, somatostatin, NSAID, allopurinol, but also non-pharmacological measures such are stenting of the pancreas canal were also attempted. Positive results of studies studying the influence of indomethacin and diclofenac and the impact of stenting on the pancreatic channel resulted in European Gastroenterology Society distinguishing these two methods as recommendations in their guidelines. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:081052
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2018-12-06 15:44:37
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