prikaz prve stranice dokumenta Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis
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Scientific paper - Review paper
Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis
Gene, 647 (2018); 48-60. https://doi.org/10.1016/j.gene.2018.01.010
Barišić, Anita; Dević Pavlić, Sanja; Ostojić, Saša; Pereza, Nina

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Barišić, A., Dević Pavlić, S., Ostojić, S. & Pereza, N. (2018). Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis. Gene, 647., 48-60. doi: 10.1016/j.gene.2018.01.010

Barišić, Anita, et al. "Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis." Gene, vol. 647, 2018, pp. 48-60. https://doi.org/10.1016/j.gene.2018.01.010

Barišić, Anita, Sanja Dević Pavlić, Saša Ostojić and Nina Pereza. "Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis." Gene 647 (2018): 48-60. https://doi.org/10.1016/j.gene.2018.01.010

Barišić, A., et al. (2018) 'Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis', Gene, 647, pp. 48-60. doi: 10.1016/j.gene.2018.01.010

Barišić A, Dević Pavlić S, Ostojić S, Pereza N. Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis. Gene [Internet]. 2018 [cited 2024 July 11];647:48-60. doi: 10.1016/j.gene.2018.01.010

A. Barišić, S. Dević Pavlić, S. Ostojić and N. Pereza, "Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis", Gene, vol. 647, pp. 48-60, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:500366. [Accessed: 11 July 2024]

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Metadata
Title (english)Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis
AuthorAnita Barišić
MBZ: 358963
AuthorSanja Dević Pavlić
AuthorSaša Ostojić
AuthorNina Pereza
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract (english)
Matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinase (TIMP) gene polymorphisms have been extensively evaluated as predisposing factors to human reproductive disorders. However, the evidence available is inconsistent. Therefore, we performed a systematic review and meta-analysis to provide the first comprehensive synopsis of case-control studies that investigated the association of MMP and TIMP gene polymorphisms with disorders that influence fertility and pregnancy complications. Literature search was performed using PubMed and Scopus databases. We included 42 case-control studies in the systematic review for the following disorders: adenomyosis, endometriosis, hypertensive disorders of pregnancy, preterm birth and recurrent spontaneous abortion. Although a large number of MMP and TIMP gene polymorphisms were tested, no exclusive and unambiguous risk factors were identified for any of the disorders. The majority of statistically significant associations were confirmed in just one study. Additionally, we performed two meta-analyses for MMP9 rs3918242 polymorphism in endometriosis/adenomyosis and preeclampsia but found no association with either disorder. Considering the modest associations and conflicting results between individual case- control studies, new data is needed for further research of this subject.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleGene
Numberingvol. 647, pp. 48-60
p-ISSN0378-1119
DOIhttps://doi.org/10.1016/j.gene.2018.01.010
URN:NBNurn:nbn:hr:184:500366
Publication2018
Document URLhttp://bib.irb.hr/917208
Document URLhttp://www.sciencedirect.com/science/article/pii/S0378111918300106
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2018-01-22 18:41:16