Vitamins and minerals are essential nutrients, which our body is unable to synthesyze by itself, but we have to ingest them with food. The lack of it is a consequence of either not consuming enough, disturbed apsorption or states in which the need of vitamins and minerals is increased. An appearal and expression of oral manifestations depends on causes of the lack of vitamins and minerals, age, common state of an indivudal. The lack of vitamins A and D will have an effect on teeth development and occural of tooth enamel hypoplasia and defects of dentin which can lead to occur of decay. The lack of vitamin K will, on the other hand, lead to gingival bleeding and the lack of vitamin C leads to deterioration of teeth supporting tissues. The oral manifestation of lacking vitamin B complex in general causes changes on the tongue and angular stomatitis. The lack of vitamin B12 and iron leads to anemia, the lack of calcium, phosphorus and magnesyum affects the growth and formation of alveoral bone. The lack of zinc leads to occural of ulcerations and postponal of wound healing. The doctor of dental medicine should be able to recognize signs and sympthoms of oral manifestations and treat them to stop their progression