The skin and the sense of touch are the earliest to develop during intrauterine development, which speaks of their importance both biologically and emotionally. Skin and brain are connected bidirectionally. Brain regions, neurotransmitter and hormonal systems associated with touch and recognition of the emotional meaning of touch, are well known. The sense of touch plays an important role in communication and conveying different emotions. Communication through touch begins intrauterine and is the first form of communication after birth. Skin-to-skin contact, child care, cuddling, hugs and other ways of stimulating the sense of touch are important for biological growth and development, as well as for psychological health. The dimension of the role of touch is best understood through examples of deprivation of this sensation. Deprivation of touch at an early age can result in delayed physical development and delayed cognitive development, as well as changes in behavior towards aggressive behavior or feelings of shame, and can reduce the chances of recovery from illness in children, especially in institutions. A number of chronic skin diseases, some functional and psychosomatic disorders and several mental disorders are associated with the deprivation of the sense of touch. In this paper, through the presentation of a patient suffering from psoriasis, we will attempt to present the link between skin and emotions on a clinical level.