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Ekologija, domaćini i vektori bakterije Francisella tularensis
Medicina Fluminensis : Medicina Fluminensis, 45 (2009), 2; 154-159. urn:nbn:hr:184:046238
Semić, Vildana; Brezovec, Martin; Lazarić, Iva; Šantić, Marina

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Semić, V., Brezovec, M., Lazarić, I. & Šantić, M. (2009). Ekologija, domaćini i vektori bakterije Francisella tularensis. Medicina Fluminensis : Medicina Fluminensis, 45. (2), 154-159. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:046238

Semić, Vildana, et al. "Ekologija, domaćini i vektori bakterije Francisella tularensis." Medicina Fluminensis : Medicina Fluminensis, vol. 45, no. 2, 2009, pp. 154-159. https://urn.nsk.hr/urn:nbn:hr:184:046238

Semić, Vildana, Martin Brezovec, Iva Lazarić and Marina Šantić. "Ekologija, domaćini i vektori bakterije Francisella tularensis." Medicina Fluminensis : Medicina Fluminensis 45, no. 2 (2009): 154-159. https://urn.nsk.hr/urn:nbn:hr:184:046238

Semić, V., et al. (2009) 'Ekologija, domaćini i vektori bakterije Francisella tularensis', Medicina Fluminensis : Medicina Fluminensis, 45(2), pp. 154-159. Available at: https://urn.nsk.hr/urn:nbn:hr:184:046238 (Accessed 26 December 2024)

Semić V, Brezovec M, Lazarić I, Šantić M. Ekologija, domaćini i vektori bakterije Francisella tularensis. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2009 June 01 [cited 2024 December 26];45(2):154-159. Available at: https://urn.nsk.hr/urn:nbn:hr:184:046238

V. Semić, M. Brezovec, I. Lazarić and M. Šantić, "Ekologija, domaćini i vektori bakterije Francisella tularensis", Medicina Fluminensis : Medicina Fluminensis, vol. 45, no. 2, pp. 154-159, June 2009. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:046238. [Accessed: 26 December 2024]

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Metadata
Title (croatian)Ekologija, domaćini i vektori bakterije Francisella tularensis
Title (english)Ecology, host and vectors of Francisella tularensis
AuthorVildana Semić
AuthorMartin Brezovec
AuthorIva Lazarić
AuthorMarina Šantić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (croatian)
Francisella tularensis aerobna je, nesporogena, gram-negativna fakultativna unutarstanična bakterija koja u ljudi i životinja uzrokuje smrtonosnu bolest tularemiju. Francizele mogu preživjeti mjesecima na niskoj temperaturi, u vodi, blatu ili leševima životinja. Ako se pohrane na -70˚C ili se liofi liziraju, virulenciju mogu zadržati godinama. Također mogu preživjeti zagrijavanje na temperaturama od 42 – 65˚C, te u hrani i vodi za piće. F. tularensis je unutarstanični parazit i sposobna je inficirati veliki broj staničnih tipova od kojih su glavni makrofagi za razmnožavanje in vivo. Postoje četiri podvrste F. tularensis: tularensis (tip A), holartica (tip B), mediasiatica i novicida. F. tularensis tip A nalazi se samo u Sjevernoj Americi i uzročnik je visoko virulentan. F. tularensis tip B je manje virulentan za zečeve, ali i za ljude, a postoji u Sjevernoj Americi i Europi. F. tularensis subsp. holartica je manje virulentna, osobito za ljude jer je diseminacija sporija i uzrokuje lakši oblik bolesti. F. tularensis subsp. mediasiatica ima jedinstvene biokemijske osobine i izolirana je samo u Kazahstanu i Turkmenistanu u središnjoj Aziji, te pokazuje virulenciju za organizme slične kao F. tularensis tip B. Primarni rezervoar tularemije su zečevi i glodavci, a vektori bolesti muhe i komarci. Uzročnik može ući u organizam na više načina i mjesta, pa tako klinička slika bolesti može biti različita.
Abstract (english)
Francisella tularensis is a gram-negative facultative intracellular bacterium that can cause a fatal disease, tularaemia, in human and animals. Francisella tularensis survives for months on very low temperatures, in water, mud or dead animals. If stored on –70° C or lyophilized, virulence can be kept for years. It can also survive heating up to 42-65° C after food or water processing. Francisella tularensis is an intercellular parasite able to infect a great number of cell types while the macrophages are considered as the key cells for manifestation of the disease in humans. There are four subtypes of Francisella tularensis: tularensis (type A), holartica (type B), mediastatica and novicida. F. tularensis type A is found only in North America and is highly virulent. F. tularensis type B is less virulent for humans, and exists in North America and Europe. F. tuleransis subsp. holartica is less virulent, especially for humans, because its dissemination is slow and it causes a mild state of illness. F. tuleransis subsp. mediastatica has unique biochemical characteristics and is isolated only in Kazakhstan and Turkmenistan in central Asia, and shows virulence for organism similar to F. tuleransis type B. The primary reservoir of tularaemia are mammals like rabbits and other rodents while the vector of disease are flies and mosquitoes. The bacteria can enter the organism by different routs of infection and the clinical symptoms of the disease depend on these entry.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numberingvol. 45, no. 2, pp. 154-159
p-ISSN0025-7729
URN:NBNurn:nbn:hr:184:046238
Publication2009-06-01
Document URLhttp://hrcak.srce.hr/38811
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-05-04 14:54:53