The quality of life is a complex and subjective concept that encompasses various aspects of experiencing and enjoying life. Recently, it has been a major research subject in numerous fields, from psychology to epidemiology. Nowadays, the importance of quality of life has been recognized, which is still under research and development. Although there is no single definition of the quality of life, for its assessment it is important to take into consideration both subjective and objective factors. The main goal of this research is to show and evaluate the women’s quality of life in relation to age, as well as assessing whether there is a difference between different age groups. The World Health Organization WHOQOL-BREF questionnaire was used for the research, which is designed to measure the quality of life of differently aged populations. The WHOQOL-BREF questionnaire provides a quality-of-life profile. It is based on a model that explains the quality of life across four domains: physical health, psychological health, social interaction, and environment. One part of the research was conducted online through a Google Forms survey that was shared on social networks intended for the population of younger women, while the other part was conducted in person by surveying older women. A total number of 164 respondents participated in the research, of which, 89 (54.3%) were younger respondents and 75 (45.7%) were older respondents. It has been observed that life satisfaction decreases with age, as well as certain domains of the quality of life. These differences in perception and experiences indicate the need for a personalized approach when creating policies and programs aimed at improving the quality of life of women in different age groups.