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master's thesis
Intenzivno liječenje trudnica s HELLP sindromom
2024. urn:nbn:hr:184:049392
Ptičar, Erika
University of Rijeka
Faculty of Medicine

Cite this document

Ptičar, E. (2024). Intenzivno liječenje trudnica s HELLP sindromom (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:049392

Ptičar, Erika. "Intenzivno liječenje trudnica s HELLP sindromom." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:049392

Ptičar, Erika. "Intenzivno liječenje trudnica s HELLP sindromom." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:049392

Ptičar, E. (2024). 'Intenzivno liječenje trudnica s HELLP sindromom', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 16 July 2024, https://urn.nsk.hr/urn:nbn:hr:184:049392

Ptičar E. Intenzivno liječenje trudnica s HELLP sindromom [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2024 [cited 2024 July 16] Available at: https://urn.nsk.hr/urn:nbn:hr:184:049392

E. Ptičar, "Intenzivno liječenje trudnica s HELLP sindromom", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:184:049392

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Metadata
TitleIntenzivno liječenje trudnica s HELLP sindromom
Title (english)Intensive treatment of pregnant women with HELLP syndrome
AuthorErika Ptičar
MentorVlatka Sotošek (mentor)
Committee memberAleks Finderle (predsjednik povjerenstva)
Committee memberMirna Bobinac (član povjerenstva)
Committee memberAlen Protić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
Rijeka
Defense date and country2024, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract
HELLP sindrom je ozbiljna komplikacija tijekom trudnoće s hemolizom, sniženim vrijednostima trombocita i povišenim vrijednostima jetrenih enzima. Etiopatogeneza HELLP sindroma nije u potpunosti poznata. Postoje brojni čimbenici rizika za razvoj HELLP sindroma. Za postavljanje dijagnoze korisna su dva klasifikacijska sustava (Tennessee i Mississippi-Triple). Simptomi su najčešće nespecifični i postoji širok spektar diferencijalne dijagnoze. Liječenje HELLP sindroma veoma je složeno i često zahtjeva multidisciplinarni pristup, osobito ako se razviju komplikacije. Komplikacije poput, diseminirane intravaskularne koagulacije, akutnog respiracijskog distres sindroma, akutne ozljede bubrega i ruptura jetre najčešće su indikacije za hospitalizaciju pacijentica u jedinice intenzivnog liječenja. Kod trudnica s HELLP sindromom i dalje je visoka stopa maternalnog mortaliteta. Pacijentici s HELLP sindromom potreban je stalni nadzor i adekvatna suportivna terapija. U jedinicama intenzivnog liječenja koriste se brojni bodovni sustavi (APACHE II, MPM, GCS, SAPS II, SOFA score) za ranu procjenu težine bolesti, ni jedan od tih sustava nije u potpunosti prilagođen opstetričkim pacijenticama.
Abstract (english)
HELLP syndrome is a serious complication durirng pregnancy associated with hemolysis, low platelets count and elevated liver enzymes. The etiopathogenesis of HELLP syndrome is not known. There are many risk factors for HELLP syndrome. Two classification systems (Tennessee and Mississippi-Triple classification) are usefull for the diagnosis of HELLP syndrome. Symptoms are often nonspecific and there are many differential diagnosis. Treatment of HELLP syndrome is complex and requires a multidisciplinary approach, especially when complications arise. Complication such as, disseminated intravascular coagulation, acute respiratory distress syndrome, acute kidney injury and liver rupture, are the most common reasons for admission to an intensive care unit (ICU). The maternal mortality rate due to HELLP syndrome is still very high. Obstetric patients with HELLP syndrome require monitoring and supportive therapy. In the intensive care unit some predictive scoring systems (APACHE II, MPM, GCS, SAPS II, SOFA score) are used as an early prognostic indicator of disease severity. These scoring systems are not fully suitable for obstetric patients.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:049392
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-06-28 08:22:05