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master's thesis
Uloga PSMA PET-CT-a u dijagnostičkoj obradi bolesnika s karcinomom prostate
2024. urn:nbn:hr:184:611063
Magdić, Ivan
University of Rijeka
Faculty of Medicine
Department of Urology

Cite this document

Magdić, I. (2024). Uloga PSMA PET-CT-a u dijagnostičkoj obradi bolesnika s karcinomom prostate (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:611063

Magdić, Ivan. "Uloga PSMA PET-CT-a u dijagnostičkoj obradi bolesnika s karcinomom prostate." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:611063

Magdić, Ivan. "Uloga PSMA PET-CT-a u dijagnostičkoj obradi bolesnika s karcinomom prostate." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:611063

Magdić, I. (2024). 'Uloga PSMA PET-CT-a u dijagnostičkoj obradi bolesnika s karcinomom prostate', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 15 July 2024, https://urn.nsk.hr/urn:nbn:hr:184:611063

Magdić I. Uloga PSMA PET-CT-a u dijagnostičkoj obradi bolesnika s karcinomom prostate [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2024 [cited 2024 July 15] Available at: https://urn.nsk.hr/urn:nbn:hr:184:611063

I. Magdić, "Uloga PSMA PET-CT-a u dijagnostičkoj obradi bolesnika s karcinomom prostate", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:184:611063

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Metadata
TitleUloga PSMA PET-CT-a u dijagnostičkoj obradi bolesnika s karcinomom prostate
Title (english)The role of PSMA PET-CT in the diagnostic work-up of patients with prostate cancer
AuthorIvan Magdić
MentorKristian Krpina (mentor)
Committee memberJosip Španjol (predsjednik povjerenstva)
Committee memberDean Markić (član povjerenstva)
Committee memberRomano Oguić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Urology)
Rijeka
Defense date and country2024, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Urology
Abstract
Karcinom prostate najčešća je maligna bolest u muškaraca. Obično je smješten u perifernoj zoni prostate, a po patohistološkom tipu je u velikoj većini slučajeva adenokarcinom. Trenutni dijagnostički protokol u svakodnevnoj kliničkoj praksi predstavljaju digitorektalni pregled, PSA, mpMR prostate i biopsija prostate. PSMA PET-CT je novija slikovna dijagnostička metoda koja se koristi za otkrivanje i praćenje karcinoma prostate. PSMA (prostata specifični membranski antigen) je transmembranski protein koji se u velikim količinama izražava na površini stanica karcinoma prostate, a njegova prisutnost omogućuje ciljano snimanje. Za razliku od konvencionalnih metoda snimanja PSMA PET-CT je osjetljiviji i specifičniji za ovaj karcinom što omogućuje ranu dijagnozu čak i pri niskim razinama PSA te preciznu lokalizaciju što je bitno za daljnje liječenje. Trenutno prema aktualnim urološkim smjernicama glavna indikacija za ovu dijagnostičku pretragu je je biokemijski recidiv, a u budućnosti je moguća i primjena u inicijalnom određivanju stadija bolesti.
Abstract (english)
Prostate cancer is the most common malignant disease in men. It is usually located in the peripheral zone of the prostate, and its histopathological type is adenocarcinoma in the vast majority of cases. The current diagnostic protocol in daily clinical practice is digitorectal examination, PSA, mpMR of the prostate and prostate biopsy. PSMA PET-CT is a newer imaging diagnostic method used to detect and monitor prostate cancer. PSMA (prostate specific membrane antigen) is a transmembrane protein that is expressed in large quantities on the surface of prostate cancer cells, and its presence enables targeted imaging. Unlike conventional imaging methods, PSMA PET-CT is more sensitive and specific for this cancer, which enables early diagnosis even at low PSA levels and precise localization, which is essential for further treatment. At the moment, according to current urological guidelines, the main indication for this diagnostic test is biochemical recurrence, and in the future it may also be used in the initial staging of the disease.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:611063
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-06-27 08:25:48