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master's thesis
Povezanost nealkoholne masne bolesti jetre i ekstrahepatalnih karcinoma
2024. urn:nbn:hr:184:212070
Bukvić, Domagoj
University of Rijeka
Faculty of Medicine
Department of Internal Medicine

Cite this document

Bukvić, D. (2024). Povezanost nealkoholne masne bolesti jetre i ekstrahepatalnih karcinoma (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:212070

Bukvić, Domagoj. "Povezanost nealkoholne masne bolesti jetre i ekstrahepatalnih karcinoma." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:212070

Bukvić, Domagoj. "Povezanost nealkoholne masne bolesti jetre i ekstrahepatalnih karcinoma." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:212070

Bukvić, D. (2024). 'Povezanost nealkoholne masne bolesti jetre i ekstrahepatalnih karcinoma', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 17 November 2024, https://urn.nsk.hr/urn:nbn:hr:184:212070

Bukvić D. Povezanost nealkoholne masne bolesti jetre i ekstrahepatalnih karcinoma [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2024 [cited 2024 November 17] Available at: https://urn.nsk.hr/urn:nbn:hr:184:212070

D. Bukvić, "Povezanost nealkoholne masne bolesti jetre i ekstrahepatalnih karcinoma", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:184:212070

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Metadata
TitlePovezanost nealkoholne masne bolesti jetre i ekstrahepatalnih karcinoma
Title (english)Association between nonalcoholic fatty liver disease and extrahepatic malignancies
AuthorDomagoj Bukvić
MentorIvana Mikolašević (mentor)
Committee memberVanja Licul (predsjednik povjerenstva)
Committee memberSanja Klobučar (član povjerenstva)
Committee memberIva Bilić Čače (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Rijeka
Defense date and country2024-07-12, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Nealkoholna masna bolest jetre trenutno predstavlja najčešći uzrok kronične jetrene bolesti u svijetu te je blisko povezana s metaboličkim sindromom. Prisutna je u 25% svjetskog stanovništva, a zbog porasta u njenoj incidenciji predstavlja golemi socioekonomski teret u globalnom zdravstvu. Promatračka istraživanja posljednjih godina pokazala su povezanost NAFLD-a s ekstrahepatalnim karcinomima, posebice s gastrointestinalnim oblicima. Povezanost je također ustanovljena bez obzira na prisutnost pretilosti, dijabetesa i metaboličkog sindroma što govori o mogućnosti NAFLD-a kao potencijalno dobrog biološkog markera za rizik od oboljevanja od ekstrahepatalnih karcinoma. Potrebno je provesti daljnja istraživanja kako bi se utvrdili mehanizmi koji su odgovorni za ovu povezanost te kako bi se uvidjelo ima li potrebe za provođenjem probira za ekstrahepatalne karcinome u osoba s NAFLD-om.
Abstract (english)
Non-alcoholic fatty liver disease is currently the most common cause of chronic liver disease in the world and is closely related to metabolic syndrome. It is present in 25% of the world's population, and due to the increase in its incidence, it represents a huge socioeconomic burden in global health. Observational studies in recent years have shown the association of NAFLD with extrahepatic cancers, especially with gastrointestinal forms. The association was also established regardless of the presence of obesity, diabetes and metabolic syndrome, which suggests the possibility of NAFLD as a potentially good biological marker for extrahepatic cancer risk. Further research is needed to determine the mechanisms responsible for this association and to see if there is a need of screening for extrahepatic cancers in people with NAFLD.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:212070
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-06-25 10:54:00