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Professional paper - Review paper
BIOPSIJA JETRE KOD HEPATITISA C
Medicina Fluminensis, 43. (2007), 2.; 138-142. urn:nbn:hr:184:936333
Kovač, Dražen

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Kovač, D. (2007). BIOPSIJA JETRE KOD HEPATITISA C. Medicina Fluminensis, 43.. (2.), 138-142. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:936333

Kovač, Dražen. "BIOPSIJA JETRE KOD HEPATITISA C." Medicina Fluminensis, vol. 43., no. 2., 2007, pp. 138-142. https://urn.nsk.hr/urn:nbn:hr:184:936333

Kovač, Dražen. "BIOPSIJA JETRE KOD HEPATITISA C." Medicina Fluminensis 43., no. 2. (2007): 138-142. https://urn.nsk.hr/urn:nbn:hr:184:936333

Kovač, D. (2007) 'BIOPSIJA JETRE KOD HEPATITISA C', Medicina Fluminensis, 43.(2.), pp. 138-142. Available at: https://urn.nsk.hr/urn:nbn:hr:184:936333 (Accessed 19 December 2024)

Kovač D. BIOPSIJA JETRE KOD HEPATITISA C. Medicina Fluminensis [Internet]. 2007 June 25 [cited 2024 December 19];43.(2.):138-142. Available at: https://urn.nsk.hr/urn:nbn:hr:184:936333

D. Kovač, "BIOPSIJA JETRE KOD HEPATITISA C", Medicina Fluminensis, vol. 43., no. 2., pp. 138-142, June 2007. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:936333. [Accessed: 19 December 2024]

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Metadata
Title (croatian)BIOPSIJA JETRE KOD HEPATITISA C
Title (english)LIVER BIOPSY IN HEPATITIS C INFECTION
AuthorDražen Kovač
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of General Pathology and Pathological Anatomy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathology
Abstract (croatian)
SAŽETAK Biopsija jetre iglom, najbolji je dijagnostički postupak koji daje uvid u stvarno oštećenje jetrenoga parenhima, ne samo kod hepatitisa C već i kod drugih bolesti koje pogađaju jetru. Materijal dobiven punkcijom koristi se uglavnom za patohistološku analizu, ali može se koristiti i za elektronsko mikroskopiranje, te za molekularnu analizu. Materijal mora biti najmanje duljine 1,5 cm i širine 0,2 cm, a određuje li se stupanj oštećenja jetre numeričkim indeksom HAI (engl. histology activity index), mora sadržavati bar 6 cjelovitih portalnih prostora. Godine 1995. Ishak i suradnici uveli su numerički indeks koji koristi grading i staging. Grading označava stupanj oštećenja jetre (piecemeal nekroze, konfluirajuće i premošćujuće nekroze, žarišne nekroze i apoptoze, te portalna upala), a staging označava promjene u građi jetre, količinu fibroze, odnosno cirozu kao krajnju fazu bolesti. Ukupni zbroj bodova kliničaru daje podatke o stanju jetrenoga tkiva, te se na osnovi toga određuje terapijski protokol.
Abstract (english)
SUMMARY Liver needle biopsy is the best diagnostic procedure to estimate a profound of liver damage, not only in Hepatitis, then in the other liver diseases. Specimen provided by liver needle biopsy is used generally for patohistological analysis, but also could be used for electron microscopy and molecular analysis. Specimen has to be 1,5 cm long and 0,2 cm wide at least and must contain 6 whole portal areas for assesing HAI (histology activity index). HAI is a numerical score for evaluation the grade of liver damage. In 1995, Ishak and colleagues were introduced a numerical score which used a terms grading and staging. Grading means the degree of liver damage (piecemeal necrosis, confluent ang bridging necrosis, focal necrosis and apoptosis, portal inflammation), staging means architectural changes, fibrosis and cirrhosis. Total score is a guideline for a clinician to choose an exact therapeutic protocol.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis
Numberingvol. 43., no. 2., pp. 138-142
p-ISSN0025-7729
URN:NBNurn:nbn:hr:184:936333
Publication2007-06-25
Document URLhttp://hrcak.srce.hr/22566
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-04-27 16:32:33