prikaz prve stranice dokumenta Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe
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Scientific paper - Original scientific paper
Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe
Toxics, 11 (2023), 10; 819. https://doi.org/10.3390/toxics11100819
Rodriguez Martin, Laura; Gilles, Liese; Helte, Emilie; Åkesson, Agneta; Tägt, Jonas; Covaci, Adrian; Sakhi, Amrit K.; Van Nieuwenhuyse, An; Katsonouri, Andromachi; Andersson, Anna-Maria; Gutleb, Arno C.; Janasik, Beata; Appenzeller, Brice; Gabriel, Catherine; Thomsen, Cathrine; Mazej, Darja; Sarigiannis, Denis; Anastasi, Elena; Barbone, Fabio; Tolonen, Hanna; Frederiksen, Hanne; Klanova, Jana; Koponen, Jani; Tratnik, Janja Snoj; Pack, Kim; Gudrun, Koppen; Ólafsdóttir, Kristin; Knudsen, Lisbeth E.; Rambaud, Loïc; Strumylaite, Loreta; Murinova, Lubica Palkovicova; Fabelova, Lucia; Riou, Margaux; Berglund, Marika; Szabados, Maté; Imboden, Medea; Laeremans, Michelle; Eštóková, Milada; Janev Holcer, Nataša; Probst-Hensch, Nicole; Vodrazkova, Nicole; Vogel, Nina; Piler, Pavel; Schmidt, Phillipp; Lange, Rosa; Namorado, Sónia; Kozepesy, Szilvia; Szigeti, Tamás; Halldorsson, Thorhallur I.; Weber, Till; Jensen, Tina Kold; Rosolen, Valentina; Puklova, Vladimira; Wasowicz, Wojciech; Sepai, Ovnair; Stewart, Lorraine; Kolossa-Gehring, Marike; Esteban-López, Marta; Castaño, Argelia; Bessems, Jos; Schoeters, Greet; Govarts, Eva More authors...

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Rodriguez Martin, L., Gilles, L., Helte, E., Åkesson, A., Tägt, J., Covaci, A. ... Govarts, E. (2023). Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe. Toxics, 11. (10). doi: 10.3390/toxics11100819

Rodriguez Martin, Laura, et al. "Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe." Toxics, vol. 11, no. 10, 2023. https://doi.org/10.3390/toxics11100819

Rodriguez Martin, Laura, Liese Gilles, Emilie Helte, Agneta Åkesson, Jonas Tägt, Adrian Covaci, Amrit K. Sakhi, et al. "Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe." Toxics 11, no. 10 (2023). https://doi.org/10.3390/toxics11100819

Rodriguez Martin, L., et al. (2023) 'Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe', Toxics, 11(10). doi: 10.3390/toxics11100819

Rodriguez Martin L, Gilles L, Helte E, Åkesson A, Tägt J, Covaci A, and sur.. Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe. Toxics [Internet]. 2023 September 28 [cited 2024 December 25];11(10). doi: 10.3390/toxics11100819

L. Rodriguez Martin, et al., "Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe", Toxics, vol. 11, no. 10, September 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:024637. [Accessed: 25 December 2024]

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Metadata
Title (english)Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe
AuthorLaura Rodriguez Martin
AuthorLiese Gilles
AuthorEmilie Helte
AuthorAgneta Åkesson
AuthorJonas Tägt
AuthorAdrian Covaci
AuthorAmrit K. Sakhi
AuthorAn Van Nieuwenhuyse
AuthorAndromachi Katsonouri
AuthorAnna-Maria Andersson
AuthorArno C. Gutleb
AuthorBeata Janasik
AuthorBrice Appenzeller
AuthorCatherine Gabriel
AuthorCathrine Thomsen
AuthorDarja Mazej
AuthorDenis Sarigiannis
AuthorElena Anastasi
AuthorFabio Barbone
AuthorHanna Tolonen
AuthorHanne Frederiksen
AuthorJana Klanova
AuthorJani Koponen
AuthorJanja Snoj Tratnik
AuthorKim Pack
AuthorKoppen Gudrun
AuthorKristin Ólafsdóttir
AuthorLisbeth E. Knudsen
AuthorLoïc Rambaud
AuthorLoreta Strumylaite
AuthorLubica Palkovicova Murinova
AuthorLucia Fabelova
AuthorMargaux Riou
AuthorMarika Berglund
AuthorMaté Szabados
AuthorMedea Imboden
AuthorMichelle Laeremans
AuthorMilada Eštóková
AuthorNataša Janev Holcer
AuthorNicole Probst-Hensch
AuthorNicole Vodrazkova
AuthorNina Vogel
AuthorPavel Piler
AuthorPhillipp Schmidt
AuthorRosa Lange
AuthorSónia Namorado
AuthorSzilvia Kozepesy
AuthorTamás Szigeti
AuthorThorhallur I. Halldorsson
AuthorTill Weber
AuthorTina Kold Jensen
AuthorValentina Rosolen
AuthorVladimira Puklova
AuthorWojciech Wasowicz
AuthorOvnair Sepai
AuthorLorraine Stewart
AuthorMarike Kolossa-Gehring
AuthorMarta Esteban-López
AuthorArgelia Castaño
AuthorJos Bessems
AuthorGreet Schoeters
AuthorEva Govarts
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Social Medicine and Epidemiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Public Health and Health Care
Abstract (english)
Human biomonitoring (HBM) data in Europe are often fragmented and collected in different EU countries and sampling periods. Exposure levels for children and adult women in Europe were evaluated over time. For the period 2000–2010, literature and aggregated data were collected in a harmonized way across studies. Between 2011–2012, biobanked samples from the DEMOCOPHES project were used. For 2014–2021, HBM data were generated within the HBM4EU Aligned Studies. Time patterns on internal exposure were evaluated visually and statistically using the 50th and 90th percentiles (P50/P90) for phthalates/DINCH and organophosphorus flame retardants (OPFRs) in children (5–12 years), and cadmium, bisphenols and polycyclic aromatic hydrocarbons (PAHs) in women (24–52 years). Restricted phthalate metabolites show decreasing patterns for children. Phthalate substitute, DINCH, shows a non-significant increasing pattern. For OPFRs, no trends were statistically significant. For women, BPA shows a clear decreasing pattern, while substitutes BPF and BPS show an increasing pattern coinciding with the BPA restrictions introduced. No clear patterns are observed for PAHs or cadmium. Although the causal relations were not studied as such, exposure levels to chemicals restricted at EU level visually decreased, while the levels for some of their substitutes increased. The results support policy efficacy monitoring and the policy-supportive role played by HBM.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleToxics
Numberingvol. 11, no. 10, 819
e-ISSN2305-6304
DOIhttps://doi.org/10.3390/toxics11100819
URN:NBNurn:nbn:hr:184:024637
Publication2023-09-28
Document URLhttps://www.mdpi.com/2305-6304/11/10/819
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-11-13 09:36:12