prikaz prve stranice dokumenta Novel Approach in Rectovaginal Fistula Treatment: Combination of Modified Martius Flap and Autologous Micro-Fragmented Adipose Tissue
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Scientific paper - Case study
Novel Approach in Rectovaginal Fistula Treatment: Combination of Modified Martius Flap and Autologous Micro-Fragmented Adipose Tissue
Biomedicines, 11 (2023), 9; 2509. https://doi.org/10.3390/biomedicines11092509
Dimova, Ana; Erceg Ivkošić, Ivana; Brlek, Petar; Dimov, Stefan; Pavlović, Tomislav; Bokun, Tomislav; Primorac, Dragan

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Dimova, A., Erceg Ivkošić, I., Brlek, P., Dimov, S., Pavlović, T., Bokun, T. & Primorac, D. (2023). Novel Approach in Rectovaginal Fistula Treatment: Combination of Modified Martius Flap and Autologous Micro-Fragmented Adipose Tissue. Biomedicines, 11. (9). doi: 10.3390/biomedicines11092509

Dimova, Ana, et al. "Novel Approach in Rectovaginal Fistula Treatment: Combination of Modified Martius Flap and Autologous Micro-Fragmented Adipose Tissue." Biomedicines, vol. 11, no. 9, 2023. https://doi.org/10.3390/biomedicines11092509

Dimova, Ana, Ivana Erceg Ivkošić, Petar Brlek, Stefan Dimov, Tomislav Pavlović, Tomislav Bokun and Dragan Primorac. "Novel Approach in Rectovaginal Fistula Treatment: Combination of Modified Martius Flap and Autologous Micro-Fragmented Adipose Tissue." Biomedicines 11, no. 9 (2023). https://doi.org/10.3390/biomedicines11092509

Dimova, A., et al. (2023) 'Novel Approach in Rectovaginal Fistula Treatment: Combination of Modified Martius Flap and Autologous Micro-Fragmented Adipose Tissue', Biomedicines, 11(9). doi: 10.3390/biomedicines11092509

Dimova A, Erceg Ivkošić I, Brlek P, Dimov S, Pavlović T, Bokun T, and sur.. Novel Approach in Rectovaginal Fistula Treatment: Combination of Modified Martius Flap and Autologous Micro-Fragmented Adipose Tissue. Biomedicines [Internet]. 2023 September 11 [cited 2024 November 22];11(9). doi: 10.3390/biomedicines11092509

A. Dimova, et al., "Novel Approach in Rectovaginal Fistula Treatment: Combination of Modified Martius Flap and Autologous Micro-Fragmented Adipose Tissue", Biomedicines, vol. 11, no. 9, September 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:868957. [Accessed: 22 November 2024]

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Metadata
Title (english)Novel Approach in Rectovaginal Fistula Treatment: Combination of Modified Martius Flap and Autologous Micro-Fragmented Adipose Tissue
AuthorAna Dimova
AuthorIvana Erceg Ivkošić
AuthorPetar Brlek
AuthorStefan Dimov
AuthorTomislav Pavlović
AuthorTomislav Bokun
AuthorDragan Primorac
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
In this paper, we introduce an innovative therapeutic approach for managing rectovaginal fistulas (RVF), by combining the modified Martius flap and micro-fragmented adipose tissue (MFAT) enriched with mesenchymal stem cells (MSC). This novel approach aims to deal with the difficulties associated with RVF, a medically complex condition with a lack of effective treatment options. We present the case of a 45-year-old female patient with a 15-year history of Crohn’s disease (CD). During the preceding eight years, she had encountered substantial difficulties resulting from a rectovaginal fistula (RVF) that was active and considerable in size (measuring 3.5 cm in length and 1 cm in width). Her condition was accompanied by tissue alterations at both the vaginal and rectal openings. Following her admission to our hospital, the patient’s case was discussed during both surgical and multidisciplinary hospital team (IRB) meetings. The team decided to combine a modified Martius flap with autologous MFAT containing MSCs. The results were remarkable, leading to comprehensive anatomical and clinical resolution of the RVF. Equally significant was the improvement in the patient’s overall quality of life and sexual satisfaction during the one-year follow-up period. The integration of the modified Martius flap with MFAT emerges as a highly promising approach for addressing CD-related RVFs that had historically been, and still are, difficult to treat, given their often refractory nature and low healing success rates.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBiomedicines
Numberingvol. 11, no. 9, 2509
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines11092509
URN:NBNurn:nbn:hr:184:868957
Publication2023-09-11
Document URLhttps://www.mdpi.com/2227-9059/11/9/2509
Type of resourceText
Access conditionsRestricted access
Terms of useLicence In copyright icon
Created on2023-09-15 12:40:23