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Scientific paper - Review paper
Celebrating 100 Years of Insulin Use
Acta clinica Croatica, 61 (2022), 3; 482-487. urn:nbn:hr:184:688549
Šakić, Zrinka; Rudež, Kristian Dominik; Radoš Kajić, Anica; Klobučar Majanović, Sanja; Rahelić, Dario

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Šakić, Z., Rudež, K. D., Radoš Kajić, A., Klobučar Majanović, S. & Rahelić, D. (2022). Celebrating 100 Years of Insulin Use. Acta clinica Croatica, 61. (3), 482-487. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:688549

Šakić, Zrinka, et al. "Celebrating 100 Years of Insulin Use." Acta clinica Croatica, vol. 61, no. 3, 2022, pp. 482-487. https://urn.nsk.hr/urn:nbn:hr:184:688549

Šakić, Zrinka, Kristian Dominik Rudež, Anica Radoš Kajić, Sanja Klobučar Majanović and Dario Rahelić. "Celebrating 100 Years of Insulin Use." Acta clinica Croatica 61, no. 3 (2022): 482-487. https://urn.nsk.hr/urn:nbn:hr:184:688549

Šakić, Z., et al. (2022) 'Celebrating 100 Years of Insulin Use', Acta clinica Croatica, 61(3), pp. 482-487. Available at: https://urn.nsk.hr/urn:nbn:hr:184:688549 (Accessed 13 May 2024)

Šakić Z, Rudež KD, Radoš Kajić A, Klobučar Majanović S, Rahelić D. Celebrating 100 Years of Insulin Use. Acta clinica Croatica [Internet]. 2022 [cited 2024 May 13];61(3):482-487. Available at: https://urn.nsk.hr/urn:nbn:hr:184:688549

Z. Šakić, K. D. Rudež, A. Radoš Kajić, S. Klobučar Majanović and D. Rahelić, "Celebrating 100 Years of Insulin Use", Acta clinica Croatica, vol. 61, no. 3, pp. 482-487, 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:688549. [Accessed: 13 May 2024]

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Metadata
Title (english)Celebrating 100 Years of Insulin Use
Title (croatian)Obilježavanje stote godišnjice prve primjene inzulina
AuthorZrinka Šakić
AuthorKristian Dominik Rudež
AuthorAnica Radoš Kajić
AuthorSanja Klobučar Majanović
AuthorDario Rahelić https://orcid.org/0000-0002-2901-0646
Author's institution(Clinical Hospital Center Rijeka)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
The year 2022 marked the one-hundredth anniversary of the first application of insulin. November 14th, the birth date of one of its main discoverers, Frederick Banting, was designated as World Diabetes Day. This paper comprises a narrative review of the history of the discovery of diabetes and insulin, progress in insulin development, important breakthroughs in insulin production and delivery, and a short commentary regarding potential future developments in insulin treatment. Diabetes, as one of the earliest recorded illnesses in medical writings, has been a focus of research for almost the entire written human history. Groundbreaking discoveries during the early 20th century have resulted in type 1 diabetes mellitus becoming a treatable, chronic condition. The relationship between good glycemic control and reduced occurrence of diabetes complications was established, which has enticed further development and refinements in insulin treatment, ranging from the purification and increased quality of insulin itself, as well as various inventions in its administration. Despite great achievements in insulin therapy so far, future research aims to avoid the need for subcutaneous administration and to create non-invasive means of insulin application.
Abstract (croatian)
Godine 2022. obilježena je stota godišnjica prve primjene inzulina. Četrnaesti studenog, datum rođenja Fredericka Bantinga, jednog od izumitelja inzulina, proglašen je Svjetskim danom dijabetesa. U ovom radu pružamo narativni pregled povijesti otkrića šećerne bolesti i inzulina, napretka u razvoju inzulina, važnih otkrića u proizvodnji i isporuci inzulina te kratak komentar o potencijalnom budućem razvoju u inzulinskoj terapiji. Šećerna bolest, kao jedna od najranijih zabilježenih bolesti u medicinskim spisima, bila je tema istraživanja tijekom gotovo cijele pisane ljudske povijesti. Revolucionarna otkrića ranog 20. stoljeća dovela su do toga da šećerna bolest tip 1 postane lječivo, kronično stanje. Kada je utvrđen odnos između dobre kontrole glikemije i smanjene pojave komplikacija šećerne bolesti, potaknuti su daljnji razvoj i usavršavanje inzulinske terapije, uključujući pročišćavanje i unapređenje kvalitete samog inzulina, kao i razne izume u njegovoj primjeni. Unatoč velikim postignućima u inzulinskoj terapiji do sada, budućim istraživanjima cilj je izbjeći potrebu za potkožnom primjenom i stvoriti neinvazivne načine primjene inzulina.
Keywords (english)
Keywords (croatian)
Languageenglish
Languagecroatian
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 61, no. 3, pp. 482-487
p-ISSN0353-9466
e-ISSN1333-9451
URN:NBNurn:nbn:hr:184:688549
Publication2022
Document URLhttps://hrcak.srce.hr/296148
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2023-08-31 08:45:42