prikaz prve stranice dokumenta A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden
  Download
PDF 1.3 MB
Scientific paper - Original scientific paper
A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden
Diagnostics, 13 (2023), 12; 2086. https://doi.org/10.3390/diagnostics13122086
Babarović, Emina; Marijić, Blažen; Vranić, Luka; Ban, Josipa; Valković, Toni; Hadžisejdić, Ita

Cite this document

Babarović, E., Marijić, B., Vranić, L., Ban, J., Valković, T. & Hadžisejdić, I. (2023). A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden. Diagnostics, 13. (12). doi: 10.3390/diagnostics13122086

Babarović, Emina, et al. "A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden." Diagnostics, vol. 13, no. 12, 2023. https://doi.org/10.3390/diagnostics13122086

Babarović, Emina, Blažen Marijić, Luka Vranić, Josipa Ban, Toni Valković and Ita Hadžisejdić. "A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden." Diagnostics 13, no. 12 (2023). https://doi.org/10.3390/diagnostics13122086

Babarović, E., et al. (2023) 'A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden', Diagnostics, 13(12). doi: 10.3390/diagnostics13122086

Babarović E, Marijić B, Vranić L, Ban J, Valković T, Hadžisejdić I. A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden. Diagnostics [Internet]. 2023 June 16 [cited 2024 May 11];13(12). doi: 10.3390/diagnostics13122086

E. Babarović, B. Marijić, L. Vranić, J. Ban, T. Valković and I. Hadžisejdić, "A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden", Diagnostics, vol. 13, no. 12, June 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:539187. [Accessed: 11 May 2024]

Please login to the repository to save this object to your list.
Metadata
Title (english)A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden
AuthorEmina Babarović
AuthorBlažen Marijić
AuthorLuka Vranić
AuthorJosipa Ban
AuthorToni Valković
AuthorIta Hadžisejdić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of General Pathology and Pathological Anatomy)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Otorhinolaryngology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Cases with low level JAK2 V617F mutations are increasingly detected; however, the clinical interpretation of the low allele JAK2 burden may be challenging. The aim of this study is to analyze and compare the bone marrow morphology and peripheral blood findings in the low level JAK2 V617F allele burden (≤15% of JAK2) and high JAK2 V617F mutation burden patients (>15% JAK2). In total, 122 JAK2 V617F positive cases with concomitant bone marrow biopsies and peripheral blood findings were re-evaluated (62 low and 60 high level JAK2 V617F positive). Within the low burden group, normal looking megakaryocytes (p = 0.0005) were more frequently found, compared with those with no atypia (p = 0.0003), their number was more frequently not increased (p = 0.009), and they did not form clusters (p = 0.001). We found statistically significant difference in the number of platelet (p = 0.0003) and hematocrit levels (p = 0.032) when comparing the JAK2 V617F
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleDiagnostics
Numberingvol. 13, no. 12, 2086
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics13122086
URN:NBNurn:nbn:hr:184:539187
Publication2023-06-16
Document URLhttps://www.mdpi.com/2075-4418/13/12/2086
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-06-19 10:38:18