prikaz prve stranice dokumenta Metallothioneins and trace elements dyshomeostasis induced by exposure to gasoline vapor in mice
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Scientific paper - Original scientific paper
Metallothioneins and trace elements dyshomeostasis induced by exposure to gasoline vapor in mice
Histology and Histopathology, 29 (2014); 407-416. urn:nbn:hr:184:380471
Grebić, Damir; Tota, Marin; Jakovac, Hrvoje; Broznić, Dalibor; Marinić, Jelena; Čanadi, Gordana; Milin, Čedomila; Radošević-Stašić, Biserka

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Grebić, D., Tota, M., Jakovac, H., Broznić, D., Marinić, J., Čanadi, G. ... Radošević Stašić, B. (2014). Metallothioneins and trace elements dyshomeostasis induced by exposure to gasoline vapor in mice. Histology and Histopathology, 29., 407-416. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:380471

Grebić, Damir, et al. "Metallothioneins and trace elements dyshomeostasis induced by exposure to gasoline vapor in mice." Histology and Histopathology, vol. 29, 2014, pp. 407-416. https://urn.nsk.hr/urn:nbn:hr:184:380471

Grebić, Damir, Marin Tota, Hrvoje Jakovac, Dalibor Broznić, Jelena Marinić, Gordana Čanadi, Čedomila Milin and Biserka Radošević Stašić. "Metallothioneins and trace elements dyshomeostasis induced by exposure to gasoline vapor in mice." Histology and Histopathology 29 (2014): 407-416. https://urn.nsk.hr/urn:nbn:hr:184:380471

Grebić, D., et al. (2014) 'Metallothioneins and trace elements dyshomeostasis induced by exposure to gasoline vapor in mice', Histology and Histopathology, 29, pp. 407-416. Available at: https://urn.nsk.hr/urn:nbn:hr:184:380471 (Accessed 01 April 2025)

Grebić D, Tota M, Jakovac H, Broznić D, Marinić J, Čanadi G, and sur.. Metallothioneins and trace elements dyshomeostasis induced by exposure to gasoline vapor in mice. Histology and Histopathology [Internet]. 2014 [cited 2025 April 01];29:407-416. Available at: https://urn.nsk.hr/urn:nbn:hr:184:380471

D. Grebić, et al., "Metallothioneins and trace elements dyshomeostasis induced by exposure to gasoline vapor in mice", Histology and Histopathology, vol. 29, pp. 407-416, 2014. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:380471. [Accessed: 01 April 2025]

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Metadata
Title (english)Metallothioneins and trace elements dyshomeostasis induced by exposure to gasoline vapor in mice
AuthorDamir Grebić
AuthorMarin Tota
AuthorHrvoje Jakovac
AuthorDalibor Broznić
AuthorJelena Marinić
AuthorGordana Čanadi
AuthorČedomila Milin
AuthorBiserka Radošević-Stašić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Physiology, Immunology and Pathophxsiology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Surgery)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Chemistry and Biochemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
To investigate the effects of air pollution related with the gasoline/petrochemical industry the expression of metallothionein I (MT-I) mRNA and tissue metals were analyzed in organs of mice, exposed to gasoline (G) vapor in laboratory conditions. Control groups consisted of intact mice and of those exposed in the metabolic chamber to fresh air. The data obtained by RT-PCR and inductively coupled plasma spectrometry have shown that exposure to G vapor leads to upregulation of MT-I mRNA in organs that receive a strong respiratory and olfactory input or participate in gasoline degradation and elimination (lungs, brain, kidney and liver). Besides, in the brain and in the lungs, kidney and liver a decreased tissue content of Zn²⁺ or Cu²⁺ and Mg²⁺ was found (p⟨0.001). Some of these changes were obtained also in mice closed in the metabolic chamber, pointing to the involvement of stress-induced mechanisms in the transcriptional regulation of MTs.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleHistology and Histopathology
Numberingvol. 29, pp. 407-416
p-ISSN0213-3911
URN:NBNurn:nbn:hr:184:380471
Publication2014
ProjectNumber: 062-0621341-0061
Title (croatian): Masne kiseline i polifenoli u regeneraciji i reparaciji tkiva.
Leader: Čedomila Milin
Jurisdiction: Croatia
Funding stream: ZP
ProjectNumber: 062-0621341-1337
Title (croatian): Morfogenetska svojstva stresnih proteina gp96 i metalotioneina
Title (english): Morphogenetic properties of heat shock protein gp96 and metallothioneins
Leader: Biserka Radošević-Stašić
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttp://bib.irb.hr/652311
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2023-05-02 07:14:08