Professional paper - Review paper
Muscle progenitor cells in skeletal muscle

Bajek, Snježana; Nikolić, Marina; Šoić Vranić, Tamara; Bajek, Marin; Marić, Ivana (2015)
Metadata
Language Croatian
Title (Croatian)Mišićne progenitorne stanice u skeletnom mišiću
Title (English)Muscle progenitor cells in skeletal muscle
AuthorBajek, Snježana
Nikolić, Marina
Šoić Vranić, Tamara
Bajek, Marin
Marić, Ivana
Abstract (Croatian)
Iako su malobrojne, satelitske stanice u skeletnom mišiću mogu u slučaju ozljede proizvesti velik broj mioblasta koji će daljnjim procesom regenerativne miogeneze dovesti do obnove mišićnog tkiva. Ove stanice su matične stanice specifične za mišićno tkivo. Njihovom aktivacijom pokreće se slijed u ekspresiji miogenetskih regulacijskih čimbenika i time program miogeneze. Satelitskim je stanicama svojstvena sposobnost samoobnavljanja. One predstavljaju heterogenu skupinu stanica s obzirom na funkciju i na markere kojima se dokazuju. Pored satelitskih stanica izolirane su i druge matične stanice u mišiću koje u eksperimentalnim uvjetima pridonose miogenezi. Miogenetski potencijal ovih stanica pokušava se iskoristiti u terapeutske svrhe u nekim oblicima mišićnih oboljenja.
Abstract (English)
Although not numerous, satellite cells in skeletal muscle are capable to generate a large number of myoblasts upon injury. A further process of regenerative myogenesis leads to the muscle regeneration. Satellite cells are stem cells specific to skeletal muscle tissue. Their activation initiates the sequence of expression in myogenic regulatory factors and thus myogenic program. Besides the ability to provide new myoblasts, these cells also have selfrenewing capacity. Satellite cells are a heterogeneous group of cells considering their function and distinction markers. Several other types of stem cells with myogenic ability (in experimental conditions) have been isolated from the skeletal muscle. Therapeutic approaches to treat some forms of muscular diseases have been based on myogenic potential of both groups of stem cells.
Keywords (Croatian)regeneracija satelitske stanice skeletni mišić
Keywords (English)regeneration satellite cells skeletal muscle
Publication typeprofessional paper - review paper
Publication statuspublished
Peer reviewpeer review
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numbering2015, Vol. 51, No. 4, pp 503-510
ISSN0025-7729
Datepublication: 01.12.2015.
Article URLhttp://hrcak.srce.hr/148292
Scientific fieldBIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Anatomy
InstitutionUniversity of Rijeka, Faculty of Medicine
(Department of Anatomy)
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:184:724885