prikaz prve stranice dokumenta Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?
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Scientific paper - Original scientific paper
Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?
Graefe's Archive for Clinical and Experimental Ophthalmology, 259 (2021), 8; 2259-2268. https://doi.org/10.1007/s00417-021-05173-5
Gilevska, Fanka; Biščević, Alma; Popović Suić, Smiljka; Bohač, Maja; Patel, Sudi

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Gilevska, F., Biščević, A., Popović Suić, S., Bohač, M. & Patel, S. (2021). Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?. Graefe's Archive for Clinical and Experimental Ophthalmology, 259. (8), 2259-2268. doi: 10.1007/s00417-021-05173-5

Gilevska, Fanka, et al. "Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?." Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 259, no. 8, 2021, pp. 2259-2268. https://doi.org/10.1007/s00417-021-05173-5

Gilevska, Fanka, Alma Biščević, Smiljka Popović Suić, Maja Bohač and Sudi Patel. "Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?." Graefe's Archive for Clinical and Experimental Ophthalmology 259, no. 8 (2021): 2259-2268. https://doi.org/10.1007/s00417-021-05173-5

Gilevska, F., et al. (2021) 'Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?', Graefe's Archive for Clinical and Experimental Ophthalmology, 259(8), pp. 2259-2268. doi: 10.1007/s00417-021-05173-5

Gilevska F, Biščević A, Popović Suić S, Bohač M, Patel S. Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?. Graefe's Archive for Clinical and Experimental Ophthalmology [Internet]. 2021 [cited 2025 April 08];259(8):2259-2268. doi: 10.1007/s00417-021-05173-5

F. Gilevska, A. Biščević, S. Popović Suić, M. Bohač and S. Patel, "Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?", Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 259, no. 8, pp. 2259-2268, 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:497144. [Accessed: 08 April 2025]

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Metadata
Title (english)Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?
AuthorFanka Gilevska
AuthorAlma Biščević
AuthorSmiljka Popović Suić
AuthorMaja Bohač
AuthorSudi Patel
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Ophthalmology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Ophthalmology
Abstract (english)
Purpose To evaluate changes in corrected distance visual acuity (CDVA), ratio of anterior and posterior corneal radii over the thinnest region of the cornea (ARC/PRC), and astigmatism after cross- linking (CXL) in keratoconus. Methods Subjective refraction and ARC/PRC (using Pentacam™) were monitored over 1 year in (I) keratoconus treated with routine CXL (n = 53), (II) relatively stable keratoconus (n = 23), and (III) age/gender matched controls (n = 24). Results CDVA (median, mode,... More interquartile range) improved significantly in group I, compared with groups II and III (p < 0.05), from 0.45 (0.60, 0.20–0.63) to 0.80 (0.95, 0.60–0.95) ; change in CDVA was associated with preop CDVA (p < 0.01 at all times postop). ARC/PRC (mean ± sd, 95% CI) changed from 1.362 (± 0.048, 1.347–1.377) to 1.425 (± 0.073, 1.401–1.449). CDVA and ARC/PRC remained stable in II and III. Significant relationships were revealed between logCDVA and ARC/PRC in I and II (at 12 months, I rs = − 0.464, II rs − 0.449) and logCDVA at postop(y), log CDVA at preop(x1), and ARC/PRC at preop(x2) in I (at 12 months, y = 0.356x1 − 1.312x2 + 1.806, r21 = 0.494, r22 = 0.203). Astigmatic power (mean ± sd, 95% CI) improved from − 3.10DC (± 1.52, − 3.55 to − 2.66) to − 2.53DC (± 1.24, − 2.90 to − 2.17) in I, and worsened from − 1.27DC (± 1.32, − 1.81 to − 0.73) to − 1.61DC (± 1.28, − 2.13 to − 1.09) in II. Vector analysis revealed in group I (a) the power of the surgically induced astigmatism (SIA) was linked to astigmatic power at preop and (b) the difference between the axis of astigmatism at preop(ø) and the axis of the SIA was linked to ø. Conclusion CXL improved CDVA, increased the ARC/PRC ratio, and modified the association between CDVA and ARC/PRC. The change in CDVA was linked to preop CDVA and ARC/PRC values. The association between SIA and preop astigmatism implies there is not a simple cause and effect relationship with CXL. Less
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleGraefe's Archive for Clinical and Experimental Ophthalmology
Numberingvol. 259, no. 8, pp. 2259-2268
p-ISSN0721-832X
DOIhttps://doi.org/10.1007/s00417-021-05173-5
URN:NBNurn:nbn:hr:184:497144
Publication2021
Document URLhttp://bib.irb.hr/1149725
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2023-02-10 08:50:50
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