prikaz prve stranice dokumenta Role of Iron and Iron Overload in the Pathogenesis of Invasive Fungal Infections in Patients with Hematological Malignancies
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Scientific paper - Review paper
Role of Iron and Iron Overload in the Pathogenesis of Invasive Fungal Infections in Patients with Hematological Malignancies
Journal of Clinical Medicine, 11 (2022), 15; 4457. https://doi.org/10.3390/jcm11154457
Valković, Toni; Damić, Marija Stanić

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Valković, T. & Damić, M. S. (2022). Role of Iron and Iron Overload in the Pathogenesis of Invasive Fungal Infections in Patients with Hematological Malignancies. Journal of Clinical Medicine, 11. (15). doi: 10.3390/jcm11154457

Valković, Toni and Marija Stanić Damić. "Role of Iron and Iron Overload in the Pathogenesis of Invasive Fungal Infections in Patients with Hematological Malignancies." Journal of Clinical Medicine, vol. 11, no. 15, 2022. https://doi.org/10.3390/jcm11154457

Valković, Toni and Marija Stanić Damić. "Role of Iron and Iron Overload in the Pathogenesis of Invasive Fungal Infections in Patients with Hematological Malignancies." Journal of Clinical Medicine 11, no. 15 (2022). https://doi.org/10.3390/jcm11154457

Valković, T. and Damić, M. S. (2022) 'Role of Iron and Iron Overload in the Pathogenesis of Invasive Fungal Infections in Patients with Hematological Malignancies', Journal of Clinical Medicine, 11(15). doi: 10.3390/jcm11154457

Valković T, Damić MS. Role of Iron and Iron Overload in the Pathogenesis of Invasive Fungal Infections in Patients with Hematological Malignancies. Journal of Clinical Medicine [Internet]. 2022 July 30 [cited 2024 December 25];11(15). doi: 10.3390/jcm11154457

T. Valković and M. S. Damić, "Role of Iron and Iron Overload in the Pathogenesis of Invasive Fungal Infections in Patients with Hematological Malignancies", Journal of Clinical Medicine, vol. 11, no. 15, July 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:116277. [Accessed: 25 December 2024]

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Metadata
Title (english)Role of Iron and Iron Overload in the Pathogenesis of Invasive Fungal Infections in Patients with Hematological Malignancies
AuthorToni Valković
AuthorMarija Stanić Damić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Iron is an essential trace metal necessary for the reproduction and survival of fungal pathogens. The latter have developed various mechanisms to acquire iron from their mammalian hosts, with whom they participate in a continuous struggle for dominance over iron. Invasive fungal infections are an important problem in the treatment of patients with hematological malignancies, and they are associated with significant morbidity and mortality. The diagnosis of invasive clinical infections in these patients is complex, and the treatment, which must occur as early as possible, is difficult. There are several studies that have shown a possible link between iron overload and an increased susceptibility to infections. This link is also relevant for patients with hematological malignancies and for those treated with allogeneic hematopoietic stem cell transplantation. The role of iron and its metabolism in the virulence and pathogenesis of various invasive fungal infections is intriguing, and so far, there is some evidence linking invasive fungal infections to iron or iron overload. Clarifying the possible association of iron and iron overload with susceptibility to invasive fungal infections could be important for a better prevention and treatment of these infections in patients with hematological malignancies.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleJournal of Clinical Medicine
Numberingvol. 11, no. 15, 4457
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm11154457
URN:NBNurn:nbn:hr:184:116277
Publication2022-07-30
Document URLhttps://www.mdpi.com/2077-0383/11/15/4457
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-08-25 10:37:29