prikaz prve stranice dokumenta Antibacterial activity of herbal extracts towards uropathogenic Enterococcus isolates as a natural approach in control of urinary tract infections
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Scientific paper - Original scientific paper
Antibacterial activity of herbal extracts towards uropathogenic Enterococcus isolates as a natural approach in control of urinary tract infections
Journal of Herbal Medicine, 28 (2021); 100445. https://doi.org/10.1016/j.hermed.2021.100445
Dimkić, Ivica; Gobin, Ivana; Begić, Gabrijela; Antić, Davorka Repac; Ristivojević, Petar; Jurica, Karlo; Berić, Tanja; Lozo, Jelena; Abram, Maja; Stanković, Slaviša

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Dimkić, I., Gobin, I., Begić, G., Antić, D. R., Ristivojević, P., Jurica, K. ... Stanković, S. (2021). Antibacterial activity of herbal extracts towards uropathogenic Enterococcus isolates as a natural approach in control of urinary tract infections. Journal of Herbal Medicine, 28.. doi: 10.1016/j.hermed.2021.100445

Dimkić, Ivica, et al. "Antibacterial activity of herbal extracts towards uropathogenic Enterococcus isolates as a natural approach in control of urinary tract infections." Journal of Herbal Medicine, vol. 28, 2021. https://doi.org/10.1016/j.hermed.2021.100445

Dimkić, Ivica, Ivana Gobin, Gabrijela Begić, Davorka Repac Antić, Petar Ristivojević, Karlo Jurica, Tanja Berić, Jelena Lozo, Maja Abram and Slaviša Stanković. "Antibacterial activity of herbal extracts towards uropathogenic Enterococcus isolates as a natural approach in control of urinary tract infections." Journal of Herbal Medicine 28 (2021). https://doi.org/10.1016/j.hermed.2021.100445

Dimkić, I., et al. (2021) 'Antibacterial activity of herbal extracts towards uropathogenic Enterococcus isolates as a natural approach in control of urinary tract infections', Journal of Herbal Medicine, 28. doi: 10.1016/j.hermed.2021.100445

Dimkić I, Gobin I, Begić G, Antić DR, Ristivojević P, Jurica K, and sur.. Antibacterial activity of herbal extracts towards uropathogenic Enterococcus isolates as a natural approach in control of urinary tract infections. Journal of Herbal Medicine [Internet]. 2021 August [cited 2024 December 31];28. doi: 10.1016/j.hermed.2021.100445

I. Dimkić, et al., "Antibacterial activity of herbal extracts towards uropathogenic Enterococcus isolates as a natural approach in control of urinary tract infections", Journal of Herbal Medicine, vol. 28, August 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:328294. [Accessed: 31 December 2024]

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Metadata
Title (english)Antibacterial activity of herbal extracts towards uropathogenic Enterococcus isolates as a natural approach in control of urinary tract infections
AuthorIvica Dimkić
AuthorIvana Gobin
AuthorGabrijela Begić
AuthorDavorka Repac Antić
AuthorPetar Ristivojević
AuthorKarlo Jurica
AuthorTanja Berić
AuthorJelena Lozo
AuthorMaja Abram
AuthorSlaviša Stanković
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (english)
Antibacterial and antibiofilm efficacy through a synergistic effect of herbal leaf extracts of bearberry (BE), bearberry tea (BTE), parsley (PE), and the strawberry tree (STE) was evaluated to discover an alternative approach to control urinary tract infections caused by Enterococci. UHPLC–DAD MS/MS analysis indicated that herbal extracts were rich in ellagic and gallic acids, catechin, quercetin, and arbutin, which are strong antioxidants. Mostly, Enterococcus faecalis isolates showed resistance only to gentamicin and/or norfloxacin (26.3 %) and moderate biofilm production (31.5 %), while 12 isolates of Enterococcus faecium showed multiple antibiotic resistance. The minimum inhibitory concentration for the majority of isolates was 1.25 mg ml−1 for STE, but 2.5 mg ml−1 for BE and BTE. Although individual extracts gave higher MIC values, for most isolates, a synergistic effect at lower concentrations was achieved, when BE or BTE (0.625 mg ml−1) was combined with STE (0.31 mg ml−1). The BTE extract was shown to have the strongest individual effect on initial adhesiveness and on biofilm formation to all selected isolates, while the synergism of BTE and STE caused significant biofilm inhibition at all concentrations tested. The synergistic effect achieved of the tested extract combinations might be a starting point in the development of alternative products, effective against antibiotic resistant Enterococcus isolates.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleJournal of Herbal Medicine
Numberingvol. 28, 100445
p-ISSN2210-8033
DOIhttps://doi.org/10.1016/j.hermed.2021.100445
URN:NBNurn:nbn:hr:184:328294
Publication2021-08
Document URLhttps://linkinghub.elsevier.com/retrieve/pii/S2210803321000257
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2022-04-05 16:43:40