prikaz prve stranice dokumenta Infection with Helicobacter pylori and long-term use of non-steroidal antiinflammatory drugs
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Scientific paper - Original scientific paper
Infection with Helicobacter pylori and long-term use of non-steroidal antiinflammatory drugs
Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, 52 (1998), 1; 27-31. urn:nbn:hr:184:687407
Včev, Aleksandar; Ivandić, Ante; Včeva, Andrijana; Štimac, Davor; Takač, Boris; Mikolasević, Ivica; Jovanović, Savo; Dmitrović, Branko; Vuković, Dubravka; Egić, Božidar

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Včev, A., Ivandić, A., Včeva, A., Štimac, D., Takač, B., Mikolasević, I. ... Egić, B. (1998). Infection with Helicobacter pylori and long-term use of non-steroidal antiinflammatory drugs. Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, 52. (1), 27-31. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:687407

Včev, Aleksandar, et al. "Infection with Helicobacter pylori and long-term use of non-steroidal antiinflammatory drugs." Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, vol. 52, no. 1, 1998, pp. 27-31. https://urn.nsk.hr/urn:nbn:hr:184:687407

Včev, Aleksandar, Ante Ivandić, Andrijana Včeva, Davor Štimac, Boris Takač, Ivica Mikolasević, Savo Jovanović, Branko Dmitrović, Dubravka Vuković and Božidar Egić. "Infection with Helicobacter pylori and long-term use of non-steroidal antiinflammatory drugs." Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske 52, no. 1 (1998): 27-31. https://urn.nsk.hr/urn:nbn:hr:184:687407

Včev, A., et al. (1998) 'Infection with Helicobacter pylori and long-term use of non-steroidal antiinflammatory drugs', Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, 52(1), pp. 27-31. Available at: https://urn.nsk.hr/urn:nbn:hr:184:687407 (Accessed 24 February 2025)

Včev A, Ivandić A, Včeva A, Štimac D, Takač B, Mikolasević I, and sur.. Infection with Helicobacter pylori and long-term use of non-steroidal antiinflammatory drugs. Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske [Internet]. 1998 [cited 2025 February 24];52(1):27-31. Available at: https://urn.nsk.hr/urn:nbn:hr:184:687407

A. Včev, et al., "Infection with Helicobacter pylori and long-term use of non-steroidal antiinflammatory drugs", Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, vol. 52, no. 1, pp. 27-31, 1998. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:687407. [Accessed: 24 February 2025]

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Metadata
Title (english)Infection with Helicobacter pylori and long-term use of non-steroidal antiinflammatory drugs
AuthorAleksandar Včev
AuthorAnte Ivandić
AuthorAndrijana Včeva
AuthorDavor Štimac
AuthorBoris Takač
AuthorIvica Mikolasević
AuthorSavo Jovanović
AuthorBranko Dmitrović
AuthorDubravka Vuković
AuthorBožidar Egić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
The use of nonsteroidal anti inflammatory drugs (NSAID) is associated with an increased risk of peptic ulcer and of ulcer complications. However, the relation between Helicobacter pylori infection and gastroduodenal damage associated with NSAID use is unclear. This study investigated the prevalence of Helicobacter pylori infection in patients with arthritis (n = 85) taking NSAID, trying to find out whether the patients taking NSAID and infected with H. pylori were more likely to have dyspepsia, mucosal damage or chronic active gastritis than those without H. pylori infection. H. pylori was identified by biopsy, rapid urease test and histologic test. Dispeptic symptoms were assessed according to a standardized questionnaire. Gastroduodenal mucosal damage was graded endoscopically (using a modified Lanza scale) and the diagnosis of chronic gastritis was based on the histologic criteria of the Sydney system. The frequency of H. pylori infection was found to increase with age. No statistically significant difference was observed in the presence of damage to gastroduodenal mucosa between the patients with and without H. pylori infection. H. pylori infection was found to be associated with an increased frequency and severity of dyspeptic symptoms in patients with arthritis taking long-term NSAID. Chronic active gastritis was only present in patients with H. pylori infection. H. pylori infection was shown to be associated with an increased frequency and severity of dyspeptic symptoms in patients with arthritis on long-term NSAID therapy, without causing an increased damage to gastroduodenal mucosa.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleActa medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske
Numberingvol. 52, no. 1, pp. 27-31
p-ISSN1330-0164
e-ISSN1848-8897
URN:NBNurn:nbn:hr:184:687407
Publication1998
Document URLhttp://bib.irb.hr/60894
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2022-03-22 14:14:00