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Scientific paper - Original scientific paper
Non-linear Optimization of Parameters in Hill Kinetics
Croatica Chemica Acta, 89 (2016), 2; 213-215. https://doi.org/10.5562/cca2863
Jeričević, Željko

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Jeričević, Ž. (2016). Non-linear Optimization of Parameters in Hill Kinetics. Croatica Chemica Acta, 89. (2), 213-215. doi: 10.5562/cca2863

Jeričević, Željko. "Non-linear Optimization of Parameters in Hill Kinetics." Croatica Chemica Acta, vol. 89, no. 2, 2016, pp. 213-215. https://doi.org/10.5562/cca2863

Jeričević, Željko. "Non-linear Optimization of Parameters in Hill Kinetics." Croatica Chemica Acta 89, no. 2 (2016): 213-215. https://doi.org/10.5562/cca2863

Jeričević, Ž. (2016) 'Non-linear Optimization of Parameters in Hill Kinetics', Croatica Chemica Acta, 89(2), pp. 213-215. doi: 10.5562/cca2863

Jeričević Ž. Non-linear Optimization of Parameters in Hill Kinetics. Croatica Chemica Acta [Internet]. 2016 [cited 2024 December 27];89(2):213-215. doi: 10.5562/cca2863

Ž. Jeričević, "Non-linear Optimization of Parameters in Hill Kinetics", Croatica Chemica Acta, vol. 89, no. 2, pp. 213-215, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:706401. [Accessed: 27 December 2024]

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Metadata
Title (english)Non-linear Optimization of Parameters in Hill Kinetics
AuthorŽeljko Jeričević
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract (english)
A novel least squares optimization of parameters in Hill enzyme kinetics has been developed. The method is based on transformation into “Michaelis-Menten like” type of equation with guaranteed convergence and the initial guess equal to zero. By using this approach, a three parameters non-linear optimization problem is transformed into a one-dimensional search for Hill’s coefficient (exponential parameter <i>n</i>). Numerical experiments illustrating feasibility of the method and quality of the solution are presented. <br><a rel="license" href="http://creativecommons.org/licenses/by/4.0/"><img alt="Creative Commons License" style="border-width:0" src="https://i.creativecommons.org/l/by/4.0/80x15.png" /></a> This work is licensed under a <a rel="license" href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatica Chemica Acta
Numberingvol. 89, no. 2, pp. 213-215
p-ISSN0011-1643
e-ISSN1334-417X
DOIhttps://doi.org/10.5562/cca2863
URN:NBNurn:nbn:hr:184:706401
Publication2016
Document URLhttps://hrcak.srce.hr/168222
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-02-28 13:35:32