prikaz prve stranice dokumenta Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia
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Scientific paper - Preliminary note / Short communication
Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia
Virus Research, 256 (2018); 90-95. https://doi.org/10.1016/j.virusres.2018.08.002
Cokarić Brdovčak, Maja; Zubković, Andreja; Ferenčić, Antun; Šoša, Ivan; Stemberga, Valter; Cuculić, Dražen; Rokić, Filip; Vugrek, Oliver; Hackenberg, Michael; Jurak, Igor

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Cokarić Brdovčak, M., Zubković, A., Ferenčić, A., Šoša, I., Stemberga, V., Cuculić, D. ... Jurak, I. (2018). Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia. Virus Research, 256., 90-95. doi: 10.1016/j.virusres.2018.08.002

Cokarić Brdovčak, Maja, et al. "Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia." Virus Research, vol. 256, 2018, pp. 90-95. https://doi.org/10.1016/j.virusres.2018.08.002

Cokarić Brdovčak, Maja, Andreja Zubković, Antun Ferenčić, Ivan Šoša, Valter Stemberga, Dražen Cuculić, Filip Rokić, Oliver Vugrek, Michael Hackenberg and Igor Jurak. "Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia." Virus Research 256 (2018): 90-95. https://doi.org/10.1016/j.virusres.2018.08.002

Cokarić Brdovčak, M., et al. (2018) 'Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia', Virus Research, 256, pp. 90-95. doi: 10.1016/j.virusres.2018.08.002

Cokarić Brdovčak M, Zubković A, Ferenčić A, Šoša I, Stemberga V, Cuculić D, and sur.. Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia. Virus Research [Internet]. 2018 [cited 2024 December 31];256:90-95. doi: 10.1016/j.virusres.2018.08.002

M. Cokarić Brdovčak, et al., "Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia", Virus Research, vol. 256, pp. 90-95, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:245977. [Accessed: 31 December 2024]

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Metadata
Title (english)Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia
AuthorMaja Cokarić Brdovčak
MBZ: 289090
AuthorAndreja Zubković
MBZ: 367491
AuthorAntun Ferenčić
AuthorIvan Šoša
AuthorValter Stemberga
AuthorDražen Cuculić
AuthorFilip Rokić
MBZ: 373032
AuthorOliver Vugrek
MBZ: 232935
AuthorMichael Hackenberg
AuthorIgor Jurak
MBZ: 229960
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Forensic Medicine and Criminalistics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Human herpes simplex virus 1 (HSV-1) expresses numerous miRNAs, the function of which is not well understood. Several qualitative and quantitative analyses of HSV-1 miRNAs have been performed on infected cells in culture and animal models, however, there is very limited knowledge of their expression in human samples. We sequenced small-RNA libraries of RNA derived from human trigeminal ganglia latently infected with HSV-1 and Varicella zoster virus (VZV) and detected only a small subset of HSV-1 miRNA. The most abundantly expressed miRNAs are miR- H2, miRNA that regulates the expression of immediate early gene ICP0, and miR-H3 and -H4, both miRNAs expressed antisense to the transcript encoding the major neurovirulence factor ICP34.5. The sequence of many HSV-1 miRNAs detected in human samples was different from the sequences deposited in miRBase, which might significantly affect targeted functional analyses.
Keywords (english)
Languageenglish
Publication typeScientific paper - Preliminary note / Short communication
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleVirus Research
Numberingvol. 256, pp. 90-95
p-ISSN0168-1702
DOIhttps://doi.org/10.1016/j.virusres.2018.08.002
URN:NBNurn:nbn:hr:184:245977
Publication2018
ProjectNumber: KK.011.1.01.0006
Title (croatian): Jačanje kapaciteta CerVirVac-a za istraživanja u virusnoj imunologiji i vakcinologiji
Leader: Stipan Jonjić
Jurisdiction: eu
ProjectNumber: N/A
Title (croatian): Centar izvrsnosti za virusnu imunologiju i cjepiva
Title (english): Centre of Excellence for Research in Viral Immunology and the Development of New Vaccines
Acronym: CERVirVac
Leader: Stipan Jonjić
Jurisdiction: Croatia
Funding stream: ZCI
Document URLhttp://bib.irb.hr/950080
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2022-02-22 07:41:38