Access restricted to higher education institution's students and staff
master's thesis
Kirurško liječenje varikoznih vena

Janko Rožić (2016)
Metadata
TitleKirurško liječenje varikoznih vena
AuthorJanko Rožić
Mentor(s)Miljenko Kovačević (thesis advisor)
Abstract
Varikozne vene su proširene, izduljene, tortuozne vene smještene u subkutisu, veličine 3mm u promjeru ili više. Patogeneza varikoznih vena je složena. U početku istraživanja, najveća važnost je pripisana inkompetentim venskim zaliscima. Daljnjim istraživanjima, otkriveni su molekularni mehanizmi oštećenja venskog zida, koji doprinose razvoju venske hipertenzije i venskog refluksa. Varikozne vene su čest problem u odrasloj populaciji, gotovo 30% ljudi je zahvaćeno. Bolest može biti asimptomatska ili simptomatska. Simptomi koji se susreću su bol, težina nogu, edem, oticanje gležnjeva i umor, svrbež, noćni grčevi, nemirne noge i kozmetski defekt. Napretak kronične venske bolesti vodi do kronične venske insuficijencije i razvoja ozbiljnijih formi bolesti, C3-6 u CEAP klasifikaciji, poput edema, lipodermatoskleroze ili ulkusa. Temeljit fizikalni pregled i DUS kao zlatni standard u procjeni morfologije vena i smještaja venskog refluksa su esencijalni za postavljanje točne dijagnoze. Liječenje se obično započinje sa konzervativnim opcijama, i cilj mu je smanjiti simptome i poboljšati izgled ekstremiteta. Uvjeti za intervencijsku terapiju su prolazak 3 mjeseca neuspješne konzervativne terapije uz pozitivan venski refluks, ili stanje po pregledu koje zahtijeva intervenciju, poput krvarenja iz varikoznih vena. Ugrubo, intervencijsku terapiju možemo podijeliti na otvorenu kirurgiju i endovenozne ablativne procedure. Prednosti otvorene kirurgije su potpuno uklanjanje varikoznih vena, čime se eliminira problem rekanalizacije. Nedostaci su mogućnost nastanka hematoma i ekhimoza, te dulji period oporavka. Moderni trendovi terapije varikoznih vena preferiraju upotrebu endovenoznih ablativnih procedura, međutim otvorena kirugija ostaje kao izvrsna metoda za liječenje.
Keywordsvaricose veins chronic venous insufficiency venous reflux DUS ligation stripping radiofrequency ablation endovenous laser ablation sclerotherapy
Committee MembersIgor Medved (committee chairperson)
Aldo Ivančić (committee member)
Alen Ružić (committee member)
GranterSveučilište u Rijeci
Medicinski fakultet
Lower level organizational unitsKatedra za kirurgiju
PlaceRijeka
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Study programme typeuniversity
Study levelintegrated undergraduate and graduate
Study programmeMedicine
Academic title abbreviationdr. med.
Genremaster's thesis
Language Croatian
Defense date2016-09-23
Parallel abstract (English)
Varicose veins are widened, elongated, tortous vein located in subcutis, their size being 3mm in diameter or more. Pathogenesis of varicose veins is complex. In the research beginnings, largest importance was attributed to incompetent venous valves. In further research, mollecular mechanisms of venous wall damage were discovered, which contribute to development of venous hypertension and venous reflux. Varicose veins are common problem in adult population, almost 30% of people are affected. The disease can be asymptomatic and symptomatic. Encountered symptoms are pain, leg heaviness, edema, itching, night cramps, restless legs and cosmetic defect. Advancement of chronic venous disease leads to chronic venous insufficiency and development of severe forms of the disease, C3-6 in CEAP classification, such as edema, lipodermatosclerosis or ulcers. Thorough physical exam and DUS as golden standard in assessment of venous morphology and location of venous reflux are essential in appointing the correct diagnosis. Treatment usually begins with conservative options, and its goal is to alleviate symptoms and improve the extremity appearance. Requirements for intervention therapy are the passing of 3 months of unsuccessful conservative therapy with positive venous reflux, or a state during examination which requires intervention, such as varicose vein hemorrhage. In rough, intervention therapy can be divided in open surgery and endovenous ablative procedures. Benefits of open surgery are complete removal of varicose veins, with which the problem of recanalization is eliminated. Shortfalls are the possibility of creating hematomas and ecchymoses., and longer recovery period. Moderns trends of varicose vein therapy prefer usage of endovenous ablative procedures, however open surgery remains as an excellent method of treatment.
Parallel keywords (Croatian)varikozne vene kronična venska insuficijencija venski refluks DUS ligacija stripping radiofrekventna ablacija endovenozna laserska ablacija skleroterapija
Resource typetext
Access conditionAccess restricted to higher education institution's students and staff
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:184:879672
CommitterBosa Licul