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Scientific paper - Original scientific paper
Comparison of calculated dose distributions reported as dose-to-water and dose-to-medium for intensity-modulated radiotherapy of nasopharyngeal cancer patients
Medical dosimetry, 43 (2018), 4; 363-369. https://doi.org/10.1016/j.meddos.2017.11.008
Smilović Radojčić, Đeni; Švabić Kolacio, Manda; Radojčić, Milan; Rajlić, David; Casar, Božidar; Faj, Dario; Jurković, Slaven

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Smilović Radojčić, Đ., Švabić Kolacio, M., Radojčić, M., Rajlić, D., Casar, B., Faj, D. & Jurković, S. (2018). Comparison of calculated dose distributions reported as dose-to-water and dose-to-medium for intensity-modulated radiotherapy of nasopharyngeal cancer patients. Medical dosimetry, 43. (4), 363-369. doi: 10.1016/j.meddos.2017.11.008

Smilović Radojčić, Đeni, et al. "Comparison of calculated dose distributions reported as dose-to-water and dose-to-medium for intensity-modulated radiotherapy of nasopharyngeal cancer patients." Medical dosimetry, vol. 43, no. 4, 2018, pp. 363-369. https://doi.org/10.1016/j.meddos.2017.11.008

Smilović Radojčić, Đeni, Manda Švabić Kolacio, Milan Radojčić, David Rajlić, Božidar Casar, Dario Faj and Slaven Jurković. "Comparison of calculated dose distributions reported as dose-to-water and dose-to-medium for intensity-modulated radiotherapy of nasopharyngeal cancer patients." Medical dosimetry 43, no. 4 (2018): 363-369. https://doi.org/10.1016/j.meddos.2017.11.008

Smilović Radojčić, Đ., et al. (2018) 'Comparison of calculated dose distributions reported as dose-to-water and dose-to-medium for intensity-modulated radiotherapy of nasopharyngeal cancer patients', Medical dosimetry, 43(4), pp. 363-369. doi: 10.1016/j.meddos.2017.11.008

Smilović Radojčić Đ, Švabić Kolacio M, Radojčić M, Rajlić D, Casar B, Faj D, and sur.. Comparison of calculated dose distributions reported as dose-to-water and dose-to-medium for intensity-modulated radiotherapy of nasopharyngeal cancer patients. Medical dosimetry [Internet]. 2018 [cited 2024 November 03];43(4):363-369. doi: 10.1016/j.meddos.2017.11.008

Đ. Smilović Radojčić, et al., "Comparison of calculated dose distributions reported as dose-to-water and dose-to-medium for intensity-modulated radiotherapy of nasopharyngeal cancer patients", Medical dosimetry, vol. 43, no. 4, pp. 363-369, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:931455. [Accessed: 03 November 2024]

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Title (english)Comparison of calculated dose distributions reported as dose-to-water and dose-to-medium for intensity-modulated radiotherapy of nasopharyngeal cancer patients
AuthorĐeni Smilović Radojčić
AuthorManda Švabić Kolacio
AuthorMilan Radojčić
MBZ: 237933
AuthorDavid Rajlić
AuthorBožidar Casar
AuthorDario Faj
MBZ: 239516
AuthorSlaven Jurković
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Medical Physics and Biophysics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Physics
Scientific / art field,
discipline and subdiscipline		INTERDISCIPLINARY AREAS OF KNOWLEDGE
Biotechnology in Biomedicine (natural science, biomedicine and healthcare, bioethics area
Abstract (english)
Advanced dose calculation algorithms for radiation therapy treatment planning can report external beam photon dose 2-sided, in terms of dose-to-medium (Dm) and dose-to-water (Dw). The purpose of our study was to determinate the effect of Dw and Dmreporting modes built in Elekta Monaco treatment planning system on intensity-modulated radiotherapy dose distributions for patients with nasopharyngeal cancer. For 13 patients involved in this retrospective study, 2 plans were created: 1 using Dw and another according to Dm reporting mode. Treatment plans were normalized such that 100% planning target volume should be covered by 95% of prescribed dose. Dose-volume constraints were assigned according to international standards. The comparison between dose distributions was performed evaluating quantities important for respective volumes of interest. For target volumes, heterogeneity index and conformity index methodology were used along with the maximum dose concept. Also, for the comparisons over particular organ at risk, maximum dose or mean dose as well as dose-volume concepts were used. For all target volumes and majority of organs at risk, the differences between 2 reporting modes are statistically insignificant, but this is not the case for bony structured organs at risks: mandible and cochlea. It was observed that Dwis higher than Dm with mean difference of 9.91% (p = 0.000009) of the mandible volume covered with 70 Gy. The same trend was observed for left and right cochlea with difference in mean dose of 8.74% (p = 0.037) and 6.87% (p = 0.029), respectively. The comparative analysis of dosimetric parameters in this study shows that the selection of reporting modes in Monaco treatment planning system can produce dose differences up to 15% in high-density volumes such as mandible and cochlea, which might have clinical consequences.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleMedical dosimetry
Numberingvol. 43, no. 4, pp. 363-369
p-ISSN0958-3947
DOIhttps://doi.org/10.1016/j.meddos.2017.11.008
URN:NBNurn:nbn:hr:184:931455
Publication2018
Document URLhttp://bib.irb.hr/916096
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2022-02-14 09:06:06