prikaz prve stranice dokumenta αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo
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Scientific paper - Original scientific paper
αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo
Journal of Dental Research, 96 (2016), 3; 323-330. https://doi.org/10.1177/0022034516678208
Vidović Zdrilić, Ivana; Banerjee, A.; Fatahi, R.; Matthews, B.G.; Dyment, N.A.; Kalajzić, I.; Mina, M.

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Vidović Zdrilić, I., Banerjee, A., Fatahi, R., Matthews, B., Dyment, N., Kalajzić, I. & Mina, M. (2016). αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo. Journal of Dental Research, 96. (3), 323-330. doi: 10.1177/0022034516678208

Vidović Zdrilić, Ivana, et al. "αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo." Journal of Dental Research, vol. 96, no. 3, 2016, pp. 323-330. https://doi.org/10.1177/0022034516678208

Vidović Zdrilić, Ivana, A. Banerjee, R. Fatahi, B.G. Matthews, N.A. Dyment, I. Kalajzić and M. Mina. "αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo." Journal of Dental Research 96, no. 3 (2016): 323-330. https://doi.org/10.1177/0022034516678208

Vidović Zdrilić, I., et al. (2016) 'αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo', Journal of Dental Research, 96(3), pp. 323-330. doi: 10.1177/0022034516678208

Vidović Zdrilić I, Banerjee A, Fatahi R, Matthews B, Dyment N, Kalajzić I, and sur.. αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo. Journal of Dental Research [Internet]. 2016 November 13 [cited 2024 November 12];96(3):323-330. doi: 10.1177/0022034516678208

I. Vidović Zdrilić, et al., "αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo", Journal of Dental Research, vol. 96, no. 3, pp. 323-330, November 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:908187. [Accessed: 12 November 2024]

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Metadata
Title (english)αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo
AuthorIvana Vidović Zdrilić
AuthorA. Banerjee
AuthorR. Fatahi
AuthorB.G. Matthews
AuthorN.A. Dyment
AuthorI. Kalajzić
AuthorM. Mina
Author's institutionUniversity of Rijeka
Faculty of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Abstract (english)
The goal of this study was to examine the contribution of perivascular cells to odontoblasts during the development, growth, and repair of dentin using mouse molars as a model. We used an inducible, Cre-loxP in vivo fate-mapping approach to examine the contributions of the descendants of cells expressing the αSMA-CreERT2 transgene to the odontoblast lineage. In vivo lineage-tracing experiments in molars showed the contribution of αSMA-tdTomato cells to a small number of newly formed odontoblasts during primary dentinogenesis. Using an experimental pulp exposure model in molars to induce reparative dentinogenesis, we demonstrate the contribution of αSMA-tdTomato cells to cells secreting reparative dentin. Our results demonstrate that αSMA-tdTomato cells differentiated into Col2.3-GFP cells composed of both Dspp odontoblasts and Bsp osteoblasts. Our findings identify a population of mesenchymal progenitor cells capable of giving rise to a second generation of odontoblasts during reparative dentinogenesis. This population also makes a small contribution to odontoblasts during primary dentinogenesis.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleJournal of Dental Research
Numberingvol. 96, no. 3, pp. 323-330
p-ISSN0022-0345
e-ISSN1544-0591
DOIhttps://doi.org/10.1177/0022034516678208
URN:NBNurn:nbn:hr:184:908187
Publication2016-11-13
Document URLhttp://journals.sagepub.com/doi/10.1177/0022034516678208
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-02-09 14:04:07