master's thesis
Šećerna bolest u dječjoj dobi

Ivana Božinović (2016)
Sveučilište u Rijeci
Medicinski fakultet
Katedra za pedijatriju
Metadata
TitleŠećerna bolest u dječjoj dobi
AuthorIvana Božinović
Mentor(s)Srećko Severinski (thesis advisor)
Abstract
Šećerna bolest predstavlja jednu od ĉešćih kroniĉnih bolesti djece. Bolest je klasificirana na ĉetiri osnovne kategorije: šećerna bolest tip 1, šećerna bolest tip 2 , drugi specifiĉni tipovi šećerne bolesti i gestacijski dijabetes. Šećerna bolest tip 1 i tip 2 su najĉešće u djeĉjoj dobi, a nastaju utjecajem genetskih i okolišnih faktora. Dijagnoza se postavlja na temelju mjerenja glukoze u krvi natašte, glukoze u krvi u bilo koje vrijeme tijekom dana, nakon testa opterećenja glukozom (OGTT) te odreĊivanjem glikoliziranog hemoglobina (Hb A1C). Klasiĉni simptomi su poliurija, polidipsija, polifagija, gubitak teţine i umor. Djeca sa šećernom bolesti tip 2 su većinom pretila i imaju veći rizik za razvoj komorbiditeta. Terapija šećerme bolesti tip 2 ukljuĉuje promjenu ţivotnih navika, gubitak teţine, fiziĉku aktivnost, te metformin. Djeca sa šećernom bolesti tip 1 lijeĉe se inzulinom. Komplikacije šećerne bolesti mogu biti akutne i kroniĉne. Akutne komplikacije su hipoglikemija, hiperglikemija i dijabetiĉka ketoacidoza. Najĉešće kroniĉne komplikacije su vaskularne i razvijaju se u odrasloj dobi. Vaskularne komplikacije su dijabetiĉaka nefropatija, retinopatija i neuropatija, te kardiovaskularne bolesti. Dijabetiĉka ketoacidoza je najozbiljnija akutna komplikacija šećerne bolesti koja zahtijeva hospitalizaciju, rehidraciju i terapiju inzulinom.
Keywordsdiabetes mellitus type 1 diabetes mellitus type 2 children diabetic ketoacidosis
Committee MembersGoran Palčevski (committee chairperson)
Harry Nikolić (committee member)
Srđan Banac (committee member)
GranterSveučilište u Rijeci
Medicinski fakultet
Lower level organizational unitsKatedra za pedijatriju
PlaceRijeka
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Study programme typeuniversity
Study levelintegrated undergraduate and graduate
Study programmeMedicine
Academic title abbreviationdr. med.
Genremaster's thesis
Language Croatian
Defense date2016-07-15
Parallel abstract (English)
Diabetes mellitus is one of the most often chronic diseases in children. It is classified into four categories: type 1, type 2, other specific types and gestational diabetes. Diabetes mellitus type 1 and dibetes mellitus type 2 are most common in children, and they are products of genes and enviromental triggers. Fasting plasma glucose level, random plasma glucose test, oral glucose tolerance test and glycated hemoglobin (Hb A1C) are used for the diagnosis of diabetes. The classic symptoms of untreated diabetes are weight loss, polyuria, polydipsia , polyphagia, weight loss and fatigue. Children with diabetes mellitus type 2 are obese and they are under higher risk to develop comorbidities. Treatment of diabetes mellitus type 2 includes lifestyle modification, weight loss, physical exercise and metformin. The menagment of diabetes mellitus type 1 in children includes insuline. Complications related to diabetes mellitus can be acute and chronic. Acute complications are hypoglikemia, hyperglikemia and diabetic ketoacidosis. Vascular complications are most common chronic complications and they become clinical in adulthood. Vascular complications include diabetic nephropathy, retinophaty, neurophaty, and cardivascular disease. Diabetic ketoacidosis is the most severe acute complication of diabetes mellitus and children with diabetic ketoacidosis require hospitalization, rehidration and insulin replacment therapy.
Parallel keywords (Croatian)šećerna bolest tip 1 šećerna bolest tip 2 djeca dijabetiĉka ketoacidoza
Resource typetext
Access conditionAccess restricted to students and staff of home institution
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:184:174366
CommitterBosa Licul