Access restricted to higher education institution's students and staff
master's thesis
Klinička obilježja djece hospitalizirane zbog Kawasakijeve bolesti

Petra Sičanica (2016)
Metadata
TitleKlinička obilježja djece hospitalizirane zbog Kawasakijeve bolesti
AuthorPetra Sičanica
Mentor(s)Srđan Banac (thesis advisor)
Abstract
Kawasakijeva bolest je multisistemska bolest nepoznate etiologije. Karakterizirana tipičnom kliničkom prezentacijom – povišena temperatura, osip, bilateralni negnojni konjuktivitis, negnojni cervikalni limfadenitis, promjene na okrajinama, hiperemija sluznice usne šupljine, suhe usnice i/ili jezik, malinast jezik. Najteţa komplikacija je razvoj aneurizmi koronarnih ţila čiju je incidenciju smanjila terapija imunoglobulinima i acetilsalicilnom kiselinom. U razdoblju od 2011.-2015. godine na Klinici za pedijatriju KBC Rijeka je hospitalizirano šestero djece s Kawasakijevom bolešću. Liječeno je 2 dječaka i 4 djevojčice. Medijan dobi je bio 27,5 mjeseci. Od kliničkih kriterija – vrućica, osip, konjuktivitis i promjene u ustima su zabiljeţeni kod sve djece, dok su promjene na ekstremitetima i limfadenitis vrata uočeni kod petero djece. Od ostalih simptoma, artritis je zabiljeţen u jednom slučaju, povraćanje kod 2 djece. Eritem BCG oţiljka je opisan kod 2 djece. Pozitivne meningealne znakove imalo je 1 dijete. EKG i ehokardiografija nisu pokazali patološki nalaz kod ni jednog djeteta. Terapija imunoglobulinom i visokim dozama acetilsalicilne kiseline provedena je kod sve djece. Prosječno je terapija salicilatima provoĎena 70 dana. Kod jednog djeteta je uočena nuspojava na imunoglobulin. Svi pacijenti su izliječeni bez posljedica.
KeywordsKawasaki disease aneurysms of the coronary vessels aspirin immunoglobulin
Committee MembersGoran Palčevski (committee chairperson)
Jelena Roganović (committee member)
Srđan Novak (committee member)
GranterSveučilište u Rijeci
Medicinski fakultet
Lower level organizational unitsKatedra za pedijatriju
PlaceRijeka
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Study programme typeuniversity
Study levelintegrated undergraduate and graduate
Study programmeMedicine
Academic title abbreviationdr. med.
Genremaster's thesis
Language Croatian
Defense date2016-07-15
Parallel abstract (English)
Kawasaki disease is a multisystem disease of unknown etiology. It is characterized by a typical clinical presentation - fever, rash, bilateral nonexudative conjunctivitis, cervical lymphadenitis, changes of the extremities, hyperemia of mucous membranes of the mouth, dry lips and/or tongue, strawberry tongue. The most serious complication is the development of aneurysms of the coronary vessels whose incidence decreased after the introduction of immunoglobulin and aspirin as therapy. In the period from 2011 to 2015 at the Department of Pediatrics at KBC Rijeka, six children were hospitalized due to Kawasaki disease. There were 2 boys and 4 girls. The median age was 27.5 months. Clinical criteria - fever, rash, conjunctivitis and changes in the mouth had all children, while changes on the extremities and neck lymphadenitis were present in five children. Among other symptoms, arthritis was recorded in one case and vomiting in 2 children. Erythema and induration at the site of BCG scar was described with 2 children. Positive meningeal signs had one child. ECG and echocardiography showed no pathological findings in any child. All children were treated with immunoglobulin therapy and high-dose aspirin. Average salicylate therapy was conducted for 70 days. Side effects of immunoglobulin were observed in one child. All the patients healed without consequences.
Parallel keywords (Croatian)Kawasakijeva bolest aneurizme koronarnih ţila acetilsalicilna kiselina IVIG
Resource typetext
Access conditionAccess restricted to higher education institution's students and staff
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:184:379267
CommitterBosa Licul