Access restricted to higher education institution's students and staff
master's thesis
Cerebralne aneurizme

Petra Posavec (2016)
Metadata
TitleCerebralne aneurizme : etiopatogeneza, simptomi, dijagnostika i liječenje
AuthorPetra Posavec
Mentor(s)Lidija Tuškan-Mohar (thesis advisor)
Abstract
Cerebralne aneurizme su patološka proširenja arterijske stijenke. Nalazimo ih u 2-3% ljudi. Poznati rizični čimbenici uključuju pušenje cigareta, hipertenziju i pozitivnu obiteljsku anamnezu. Hemodinamika već godinama igra ključnu ulogu u stvaranju i razvoju cerebralnih aneurizmi. Nerupturirane cerebralne aneurizme su češće u žena u omjeru 3:1 . Cerebralne aneurizme možemo podijeliti prema veličini i obliku.Tri glavna oblika su vrećaste, vretenaste i difuzne aneurizme. Cerebralne aneurizme su sporadične lezije, međutim, rijetke su obiteljske forme cerebralnih aneurizmu povezane s autosomno-dominantom policističnom bolesti bubrega tipa IV, Ehlers-Danlos sindromom, moyamoya bolešću i arteriovenskim malformacijama mozga. Cerebralne aneurizme su najčešće smještene u prednjoj moždanoj cirkulaciji. Većina je cerebralnih aneurizmi asimptomatska dok ne rupturiraju. Međutim, nerupturirane aneurizme mogu postati simptomatske. Simptomi uključuju glavobolju, neuropatije kranijalnih živaca i disfunkciju piramidnog trakta. Najčešće se cerebralne aneurizme prezentiraju subarahnoidalnim krvarenjem. Dijagnoza SAH-a se uglavnom postavlja CT-om, CT ili kateter angiografijom. Cerebralne aneurizme, nerupturirane ili rupturirane, mogu se liječiti otvorenom operacijom i endovaskularno, ili kombinacijom te dvije metode. Kirurško „klipiranje“ ili endovaskularno postavljanje uzvojnice su najčešće korištene tehnike u liječenje cerebralnih aneurizmi. U većini slučajeva, anatomski čimbenici, kao što su veličina i lokalizacija, određuju koja će metoda liječenja biti najpogodnija za pacijenta.
Keywordscerebral aneurysm rupture hemodynamics subarachnoid hemorrhage
Committee MembersIgor Antončić (committee chairperson)
Mira Bučuk (committee member)
Darko Ledić (committee member)
GranterSveučilište u Rijeci
Medicinski fakultet
Lower level organizational unitsKatedra za neurologiju
PlaceRijeka
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Study programme typeuniversity
Study levelintegrated undergraduate and graduate
Study programmeMedicine
Academic title abbreviationdr. med.
Genremaster's thesis
Language Croatian
Defense date2016-07-15
Parallel abstract (English)
Cerebal aneurysms are pathological dilatations of the arterial walls. They occur in 2-3% of humans. Known risk factors include smoking, hypertension and postive family history for intracranial aneurysms. Hemodynamics has been proposed for many years as a fundamental player in the process of aneurysms formation and progression.Unruptured intracranial aneurysms are more common in women with a 3:1 ratio of women to men. Cerebral aneurysms are classified both by size and shape. The 3 major types of true intracranial aneurysms are saccular, fusiform, and diffuse. Intracranial aneurysms are sporadically lesions; however, a rare familial form has been associated with conditions like autosomal dominant polycystic kidney disease, Ehlers-Danlos syndrome type IV, moyamoya disease and arteriovenous malformations of the brain. Aneurysms located in the anterior circulation are more frequent. Most aneurysms do not cause symptoms until they rupture. Some unruptured aneurysms can become symptomatic. Symptoms include headache, cranial neuropathies and pyramidal tract disfunction. The most common presentation of intracranial aneurysm is subarachnoid hemorrhage.Diagnosis of SAH is primarily by CT, CT or catheter angiography. Aneurysms, whether ruptured on unruptured, can be treated by open surgery or endovasculary, or by combining these two modalities. Surgical clipping and endovascular coiling are the most commonly used techniques for aneurysm treatment. In many cases, anatomic considerations, such as size or location determine which treatment is most approppriate for the patient.
Parallel keywords (Croatian)cerebralne aneurizme ruptura hemodinamika subarahnoidalno krvarenje
Resource typetext
Access conditionAccess restricted to higher education institution's students and staff
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:184:887628
CommitterBosa Licul