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master's thesis
Incidencija, klinička evaluacija i kirurško liječenje bolesnika s karcinomom bubrega

Iva Vrsaljko (2016)
Metadata
TitleIncidencija, klinička evaluacija i kirurško liječenje bolesnika s karcinomom bubrega
AuthorIva Vrsaljko
Mentor(s)Dean Markić (thesis advisor)
Abstract
Uvod: Karcinom bubrega je zbog visoke učestalosti i mortaliteta jedan od najznačajnijih tumora urogenitalnog sustava. Svrha rada: Svrha rada je prikazati incidenciju karcinoma bubrega i njegove kliničke značajke u pacijenata koji su liječeni kirurški. Ispitanici i metode: Od 01. siječnja 1972. do 31. prosinca 2012. u Kliničkom bolničkom centru Rijeka je zbog karcinoma bubrega operirano 1045 bolesnika. Retrospektivno su analizirani njihovi opći demografski podaci, kliničko-patološki podaci i preživljenje. Rezultati: Tijekom vremena je došlo do značajnog povećanja broja bolesnika, s 5 pacijenata godišnje početkom 70-tih godina na preko 50 posljednjih nekoliko godina. Broj asimptomatskih bolesnika se povećao sa 6% na 75%. Prosječna dob bolesnika bila je 63,2 godine (raspon 21-86 godina). Nefrektomija je učinjena u 95,3% bolesnika, u 2,6% parcijalna nefrektomija, a u 2,1% eksplorativna lumbotomija. U promatranom razdoblju 5-godišnje preživljenje je bilo 64%, a 10-godišnje preživljenje 47%. Zaključak: Učestalost karcinoma bubrega se višestruko povećala tijekom posljednja četiri desetljeća. Novije dijagnostičke metode omogućuju njegovo otkrivanje u ranijoj fazi, a samim time se omogućuje poštednije kirurško liječenje ne umanjujući onkološki učinak.
KeywordsRenal cell cancer – epidemiology diagnosis surgery Diagnostic imaging – diagnosis Nephrectomy – methods Survival – statistics and numerical data.
Committee MembersJosip Španjol (committee chairperson)
Romano Oguić (committee member)
Gordana Đorđević (committee member)
GranterSveučilište u Rijeci
Medicinski fakultet
Lower level organizational unitsKatedra za kirurgiju
PlaceRijeka
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Urology
Study programme typeuniversity
Study levelintegrated undergraduate and graduate
Study programmeMedicine
Academic title abbreviationdr. med.
Genremaster's thesis
Language Croatian
Defense date2016-07-15
Parallel abstract (English)
Introduction: Beacuse of its high incidence and mortality rate renal cell cancer (RCC) is one of the most important urogenital tumors. Purpose: To present the incidence of renal cell cancer and its clinical features in patients who underwent surgery. Patients and Methods: From 01 January 1972 to 31 December 2012 in Clinical Hospital Center Rijeka 1045 patients were operated because of RCC. Their general demographic data, clincal-pathological data and survival were retrospectively analyzed. Results: Number of operated patients has significantly increased during time; from 5 in the beginning of the seventies to more than 50 in the last few years. The number of asymptomatic patients has increased from 6% to 75%. The mean age of patients was 63.2 years (range 21-86). Nephrectomy was preformed in 95.3% patients, nephron sparing surgery in 2.6% and explorative lumbotomy in 2.1% of patients. The 5-year survival was 64% and 10-year survival 47%. Conclusion: The incidence of RCC has substantially increased during the last four decades. The new diagnostic methods can find renal cell cancer in an earlier phase so the nephron sparing surgery can be performed without negative influence on oncological outcome.
Parallel keywords (Croatian)Karcinom bubrega – epidemiologija dijagnoza kirurško liječenje Dijagnostičke metode – dijagnoza Nefrektomija – metode Preživljenje – statistika i numerički podaci.
Resource typetext
Access conditionAccess restricted to higher education institution's students and staff
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:184:428907
CommitterBosa Licul