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Professional paper - Review paper
Nasljedna trombofilija
Medicina Fluminensis, 57 (2021), 1; 56-63. https://doi.org/10.21860/medflum2021_365327
Baumgartner, Petra; Valković, Toni

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Baumgartner, P. & Valković, T. (2021). Nasljedna trombofilija. Medicina Fluminensis, 57. (1), 56-63. doi: 10.21860/medflum2021_365327

Baumgartner, Petra and Toni Valković. "Nasljedna trombofilija." Medicina Fluminensis, vol. 57, no. 1, 2021, pp. 56-63. https://doi.org/10.21860/medflum2021_365327

Baumgartner, Petra and Toni Valković. "Nasljedna trombofilija." Medicina Fluminensis 57, no. 1 (2021): 56-63. https://doi.org/10.21860/medflum2021_365327

Baumgartner, P. and Valković, T. (2021) 'Nasljedna trombofilija', Medicina Fluminensis, 57(1), pp. 56-63. doi: 10.21860/medflum2021_365327

Baumgartner P, Valković T. Nasljedna trombofilija. Medicina Fluminensis [Internet]. 2021 March 01 [cited 2024 May 07];57(1):56-63. doi: 10.21860/medflum2021_365327

P. Baumgartner and T. Valković, "Nasljedna trombofilija", Medicina Fluminensis, vol. 57, no. 1, pp. 56-63, March 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:726445. [Accessed: 07 May 2024]

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Metadata
Title (croatian)Nasljedna trombofilija
Title (english)Inherited thrombophilia
AuthorPetra Baumgartner
AuthorToni Valković
Author's institutionUniversity of Rijeka
Faculty of Health Studies
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (croatian)
Pojam trombofilija podrazumijeva nasljedne i/ili stečene poremećaje sustava zgrušavanja krvi koji predisponiraju razvoj tromboze. Nasljedna trombofilija obuhvaća stanja u kojima naslijeđene genetske mutacije dovode do abnormalne količine ili funkcije proteina uključenih u sustav koagulacije, što za posljedicu može imati povećanu sklonost venskim i, znatno rjeđe, arterijskim trombozama. Nedvojbeno definirana nasljedna trombofilna stanja nedostatak su antitrombina, proteina C i proteina S te pojava faktora V Leiden i protrombinskih varijanti. Još uvijek ne postoje jednoznačne preporuke za testiranje nasljedne trombofilije, a profilaksa i liječenje tromboembolijskih događaja moraju biti individualizirani.
Abstract (english)
The term thrombophilia implies inherited and/or acquired disorders of the hemostasis mechanism that predispose to the development of thrombosis. Inherited thrombophilia includes conditions in which an inherited genetic mutations affect the amount or function of proteins involved in the coagulation system, and as a consequence, an increased tendency to venous and, much less frequently, arterial thrombosis. Undoubtedly defined inherited thrombophilic conditions are the deficiency of antithrombin, protein C and protein S and the appearance of factor V Leiden and rothrombin's variants. There is still no clear recommendation for testing hereditary thrombophilia, and the prophylaxis and the treatment of thromboembolic events must be individualized.
Keywords (croatian)
Keywords (english)
Languagecroatian
Languageenglish
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis
Numberingvol. 57, no. 1, pp. 56-63
p-ISSN1847-6864
e-ISSN1848-820X
DOIhttps://doi.org/10.21860/medflum2021_365327
URN:NBNurn:nbn:hr:184:726445
Publication2021-03-01
Document URLhttps://hrcak.srce.hr/251266
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2021-03-03 18:20:54