prikaz prve stranice dokumenta Primjena trombocitima bogatog fibrina u parodontologiji i dentalnoj medicini
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master's thesis
Primjena trombocitima bogatog fibrina u parodontologiji i dentalnoj medicini
2016. urn:nbn:hr:184:396613
Matoš, Ivan
University of Rijeka
Faculty of Medicine

Cite this document

Matoš, I. (2016). Primjena trombocitima bogatog fibrina u parodontologiji i dentalnoj medicini (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:396613

Matoš, Ivan. "Primjena trombocitima bogatog fibrina u parodontologiji i dentalnoj medicini." Master's thesis, University of Rijeka, Faculty of Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:184:396613

Matoš, Ivan. "Primjena trombocitima bogatog fibrina u parodontologiji i dentalnoj medicini." Master's thesis, University of Rijeka, Faculty of Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:184:396613

Matoš, I. (2016). 'Primjena trombocitima bogatog fibrina u parodontologiji i dentalnoj medicini', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 18 November 2024, https://urn.nsk.hr/urn:nbn:hr:184:396613

Matoš I. Primjena trombocitima bogatog fibrina u parodontologiji i dentalnoj medicini [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2016 [cited 2024 November 18] Available at: https://urn.nsk.hr/urn:nbn:hr:184:396613

I. Matoš, "Primjena trombocitima bogatog fibrina u parodontologiji i dentalnoj medicini", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:184:396613

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Metadata
TitlePrimjena trombocitima bogatog fibrina u parodontologiji i dentalnoj medicini
AuthorIvan Matoš
MentorDavor Kuiš (mentor)
MBZ: 247451
GranterUniversity of Rijeka
Faculty of Medicine
Rijeka
Defense date and country2016, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Abstract
Trombocitima bogat fibrin (PRF) je trombocitni koncentrat s 3D-strukturom (fibrinska mrežica) u kojoj su uklopljeni trombociti, faktori rasta i citokini, koji mogu biti otpušteni nakon nekog vremena. To je autologni krvni derivat koji povoljno djeluje na hemostazu i regeneraciju tkiva. Sadrži faktore rasta kao što su faktor rasta porijeklom iz trombocita (PDGF), transformirajući faktor rasta (TGF-β1) i faktor rasta sličan inzulinu (IGF-I i IGF-II) koji sudjeluju u staničnoj migraciji, proliferaciji i diferencijaciji. PRF predstavlja drugu generaciju trombocitnih koncentrata, predstavljenu 2001. Produkti trombocita koriste se u terapiji kliničkih slučajeva koji zahtijevaju cijeljenje rane i regeneraciju tkiva. Neka područja njihove primjene uključuju: parodontnu, oralnu, maksilofacijalnu i plastičnu kirurgiju, otorinolaringologiju, ortopediju i dermatologiju. PRF se može kombinirati s drugim regenerativnim tehnikama. Područja primjene PRF-a u dentalnoj medicini su: vođena regeneracija kostiju, vođena regeneracija tkiva, cijeljenje mekih tkiva u mukogingivalnoj kirurgiji te revitalizacija zuba s nekrotičnom pulpom i nezavršenom apeksogenezom. Najveće prednosti upotrebe PRF-a su: dostupnost pacijentima, jednostavnost pripreme i minimalna trauma.
Abstract (english)
Platelet Rich Fibrin (PRF) is a platelet concentrate with a three dimensional architecture (fibrin matrix) in which platelets, growth factors and cytokines are trapped and may be released after a certain time. It is an autologous blood-derived biomaterial which favor hemostasis and tissue repair. It contains growth factors like platelet derived growth factor (PDGF), transforming growth factor β1 (TGF β1) and insulin like growth factor (IGF-I and IGF-II) that are involved in cell migration, cell proliferation and cell differentiation. PRF is the second-generation of platelet concentrates, first presented in 2001. Platelet products are used for clinical and surgical applications which require hemostasis and tissue regeneration. Some fields in which it may be used are: periodontal, oral, maxillo-facial and plastic surgery, otorhinolaryngology, orthopedic and dermatology. PRF can be combined with other regenerative techniques. Areas of PRP application in dental medicine are: guided bone regeneration, guided tissue regeneration, healing of the soft tissue in mucogingival surgery and revitalization of tooth with necrotic pulp and open apex. The most significant advantages of PRF are: availability to patients, ease of preparation and minimized trauma.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:396613
Study programmeTitle: Dental Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2016-07-22 10:14:06