Introduction: Dystonia is a movement disorder characterised by continuous or interrupted muscle contractions causing abnormal, often repeating movements, posture or both. Dystonia is not easy to recognize especially when the symptoms are mild or isolated so the disease is often misdiagnosed. Although pathogenesis-oriented treatment is desirable for now it is only symptomatic due to lack of knowledge of the exact pathogenetic mechanism. The purpose of this review is to identify long-term outcomes of DBS for dystonia and analyze wether genetic etiology has any influence on the outcomes. Discussion: From the isolated dystonia group it seems that patients with DYT1 dystonia respond best to DBS while DYT6 patients respond less robust even in patients with contractures. Excellent long-term outcomes are also described in patients with Meige syndrome,DYT25, DYT24 and tardive dystonia. From the combined dystonia group it seems that patients with DYT16, DYT3 and DYT11 have good long-term outcomes while DBS seems to have no influence in DYT12 patients. Furthermore, it seems that genetic status influences the DBS outcome which means that genetic testing has value in objectively confirming the diagnosis and predicting DBS outcomes while providing insight into dystonia pathogenesis and developing new leads for DBS targets. Moreover, it is important to mention that psychiatric diseases have a significant prevalence among dystonia patients, but more importantly, a significant impact on the patients' quality of life. Therefore it is of grave importance to also asses non-motor outcomes of DBS in the future. Conclusion: Systematic and multicentric studies with homogenous patient groups are needed to definetly discern the influence of genetics on DBS.